Results 81 to 90 of about 10,499,951 (250)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Vibrio Cholerae Organism:

open access: yes, 2014
Vibrio cholerae is a gram negative, curved, mobile bacillus with many serogroups. Only serogroups O1 and O139 cause clinical cholera associated with enterotoxin. Usually is 1 to 3 days, with a range of a few hours to 5 days.
Infectious Period, Incubation Period
core  

Age-period-cohort model trend analysis of maternal mortality.

open access: yes, 2020
Age-period-cohort model trend analysis of maternal mortality.
Tippawan Liabsuetrakul (6646876)   +3 more
core   +1 more source

Modification of the refractive index response of long period gratings using thin film overlays. [PDF]

open access: yes, 2005
The response of a fibre optic long period grating (LPG) to the surrounding refractive index is shown to be modified by the deposition of a thin film of thickness of order 100 nm onto the cladding.
Ishaq Imran, M   +4 more
core   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Optical fibre long period grating based selective vapour sensing of volatile organic compounds [PDF]

open access: yes, 2010
The chemical sensing capabilities of an optical fibre long period grating (LPG) coated with a functional material are explored. The LPG period and coating thickness are chosen such that the mode transition region, characteristic of LPGs coated with ...
Tatam, Ralph P.   +4 more
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Response of fibre optic long period gratings operating near the phase matching turning point to the deposition of nanostructured coatings. [PDF]

open access: yes, 2008
The response of the dual resonant bands of a fibre optic long period grating operating near the phase matching turning point to the deposition of a nanostructured coating is investigated. The dual resonant bands are observed to show a high sensitivity to
Tatam, Ralph P.   +3 more
core   +1 more source

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