Results 31 to 40 of about 94,247 (290)

Is Canakinumab Safe During Pregnancy? New Insights from Three Cases in Slovakia

Biologics
Background and Objectives: Canakinumab, a human recombinant monoclonal antibody against interleukin-1ß (IL-1ß), is indicated for the treatment of selected autoinflammatory periodic fever syndromes and rheumatic diseases.
Branislav Slenker, Katarina Hrubiskova, Lenka Kapustova, Anna Bobcakova, Juraj Ondris, Milos Jesenak   +5 more
doaj   +1 more source

An adult case of atypical familial Mediterranean fever (pyrin‐associated autoinflammatory disease) similar to adult‐onset Still’s disease

Clinical Case Reports, 2019
Key Clinical Message We present a 55‐year‐old woman with periodic fever and symptoms similar to adult‐onset Still's disease (AOSD). She had a heterogeneous mutation of the MEFV gene and colchicine was effective.
Hayato Tsuruma, Hiroe Sato, Eriko Hasegawa, Yukiko Nozawa, Takeshi Nakatsue, Yoko Wada, Takeshi Kuroda, Yoshiki Suzuki, Masaaki Nakano, Ichiei Narita   +9 more
doaj   +1 more source

The Clinical Chameleon of Autoinflammatory Diseases in Children

Cells, 2022
The very first line of defense in humans is innate immunity, serving as a critical strongpoint in the regulation of inflammation. Abnormalities of the innate immunity machinery make up a motley group of rare diseases, named ‘autoinflammatory’, which are ...
Eugenio Sangiorgi, Donato Rigante
doaj   +1 more source

PERIODIC FEVER SYNDROME (MEVALONATE KINASE DEFICIENCY, HYPERIMMUNOGLOBULINEMIA D SYNDROME) IN CHILDREN

Вопросы современной педиатрии, 2012
Periodic fever syndrome with mevalonate kinase deficiency, also known as hyperimmunoglobulinemia D syndrome, is characterized by early onset and relatively benign course.
Yu. S. Patrusheva, M. D. Bakradze
doaj   +1 more source

Tumor necrosis factor receptor-associated cycle syndrome: a case report and literature review

Frontiers in Pediatrics, 2023
Recurring episodes of fever characterize tumor necrosis factor receptor-associated periodic syndrome (TRAPS) which is autosomal dominant. The primary symptoms of patients with TRAPS include prolonged fever, abdominal pain, muscle pain, and skin rashes ...
Ziwei Li, Xiaoping Jing, Shuya Zhang, Tiantian Liu, Qingyin Guo   +4 more
doaj   +1 more source

Low Dose Daily Iron Supplementation Improves Iron Status and Appetite but not Anemia, Whereas Quarterly Anthelminthic Treatment Improves Growth, Appetite and Anemia in Zanzibari Preschool Children. [PDF]

, 2004
Iron deficiency and helminth infections are two common conditions of children in developing countries. The consequences of helminth infection in young children are not well described, and the efficacy of low dose iron supplementation is not well ...
Adam, Albonico, Albonico, Antonio Montresor, Brown, Caulfield, Crompton, Davis, de Andraca, Dickson, Diggle, Donnen, Freij, Greenberg, Gupta, Gupta, Hababu M. Chway, Idjradinata, James M. Tielsch, Jape Khatib Jape, Jelkmann, Kloetzel, Lackritz, Langhans, Levin, Lorenzo Savioli, Lozoff, Marco Albonico, Menendez, Montresor, National Research Council, Nelson, Pelletier, Pinero, Plata-Salaman, Rebecca J. Stoltzfus, Reeds, Rosenberg, Rousham, Savioli, Schultz, Smith, Solomons, Stoltzfus, Stoltzfus, Stoltzfus, Stoltzfus, Thein-Hlaing, Trape, Verhoef, Warren, Willett, World Health Organization, World Health Organization Expert Committee   +53 more
core   +1 more source

An Up-to-date Approach to a Patient with a Suspected Autoinflammatory Disease

Rambam Maimonides Medical Journal, 2017
Autoinflammatory diseases (AID) are characterized by seemingly unprovoked self-limited attacks of fever and systemic inflammation potentially leading to amyloidosis. Familial Mediterranean fever (FMF) is the most common AID and therefore the most studied.
Merav Lidar, Eitan Giat
doaj   +1 more source

The Role of Invasive Procedures in the Treatment of Complicated Gastrointestinal Graft‐Versus‐Host Disease in Pediatric Patients

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Gastrointestinal graft‐versus‐host disease (GI GVHD) following hematopoietic stem cell transplant is typically managed with medical therapy, but surgery and angioembolization may be warranted in selected cases with life‐threatening complications.
Gaia Brunetti, Giorgio Persano, Chiara Grimaldi, Pier Luigi Di Paolo, Carmen Malaspina, Francesco Quagliarella, Valerio Balassone, Anna Chiara Iolanda Contini, Gian Luigi Natali, Rita Alaggio, Ivan Pietro Aloi, Tamara Caldaro, Alessandro Crocoli   +12 more
wiley   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Air Pollution and the Risk and Progression of Multiple Sclerosis: A Systematic Review and Meta‐Analysis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose Air pollution has been linked to several neurological conditions, including stroke and neurodegenerative diseases. Evidence regarding its association with multiple sclerosis (MS) remains conflicting, limited by small sample sizes. Methods PubMed, Embase, Scopus, and Cochrane controlled register of trials (CENTRAL) were searched on ...
Ahmad A. Toubasi, Thuraya N. Al‐Sayegh
wiley   +1 more source