Clinical and functional characterisation of a novel TNFRSF1A c.605T > A/V173D cleavage site mutation associated with tumour necrosis factor receptor-associated periodic fever syndrome (TRAPS), cardiovascular complications and excellent response to etanercept treatment. [PDF]
Objectives: To study the clinical outcome, treatment response, T-cell subsets and functional consequences of a novel tumour necrosis factor (TNF) receptor type 1 (TNFRSF1A) mutation affecting the receptor cleavage site.
B H Belohradsky +7 more
core +1 more source
The use of an interleukin 1 inhibitor in a patient with atypical course of periodic fever
The article presents a case of periodic fever (PF) in a 35-year-old patient, who did not have hereditary and proven genetic factors of the disease, which was characterized by an atypical course with variable in duration and frequency severe abdominal ...
M. S. Eliseev +10 more
doaj +1 more source
Periodic fever with pharyngitis, aphthous stomatitis and cervical adenitis (PFAPA syndrome) is a common cause of periodic fever in children and usually manifests as episodes of fever recurring with a clockwork periodicity. Although rare after adolescence,
Diogo Paixão Marques +3 more
doaj +1 more source
Febre periódica: síndroma hiper-IgD--primeiro caso em Portugal.
Periodic fever can have one of multiple causes. Among the hereditary periodic fever syndromes, hyper-IgD syndrome (HIDS) is a possible diagnosis, although, until now, no cases had been described in Portugal.We report a 25-year-old woman, with periodic ...
Tiago Tribolet de Abreu
doaj +1 more source
Natural history and outcome in systemic AA amyloidosis [PDF]
BACKGROUND:Deposition of amyloid fibrils derived from circulating acute-phase reactant serum amyloid A protein (SAA) causes systemic AA amyloidosis, a serious complication of many chronic inflammatory disorders.
Gallimore, JR +6 more
core +1 more source
The periodic fever syndromes are autoinflammatory diseases that present with recurrent fever, serositis and rash. Familial Mediterranean fever is the most common periodic fever syndrome and characterized by recurrent attacks of fever, arthritis ...
Mustafa Çakan +3 more
doaj +1 more source
Envelope Determinants of Equine Lentiviral Vaccine Protection [PDF]
Lentiviral envelope (Env) antigenic variation and associated immune evasion present major obstacles to vaccine development. The concept that Env is a critical determinant for vaccine efficacy is well accepted, however defined correlates of protection ...
A Kumar +76 more
core +12 more sources
Plant-Based Insect Repellents: A Review Of Their Efficacy, Development and Testing. [PDF]
Plant-based repellents have been used for generations in traditional practice as a personal protection measure against host-seeking mosquitoes. Knowledge on traditional repellent plants obtained through ethnobotanical studies is a valuable resource for ...
Maia, Marta Ferreira, Moore, Sarah J
core +5 more sources
Reimann's "Habitual Hyperthermia" Responding to Hormone Therapy. [PDF]
A 25-year-old woman presented with fever of unknown origin, exhibiting malaise and low-grade fevers in evenings. These fevers exhibited a pattern of starting mid-menstrual cycle with resolution around the onset of menses, matching a pattern of "habitual ...
Currier, Judith S, Yang, Otto O
core +2 more sources
Hereditary Systemic Autoinflammatory Diseases: Therapeutic Stratification
Hereditary systemic autoinflammatory diseases (SAIDs) are rare, often severe conditions characterised by mutations in the key regulators of innate immune responses.
Ovgu Kul Cinar +8 more
doaj +1 more source

