Results 41 to 50 of about 710,498 (297)

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

What Is PFAPA and Why Does it Matter?

Journal of Patient-Centered Research and Reviews, 2014
PFAPA, the syndrome of periodic fever, aphthous stomatitis, pharyngitis and cervical lymphadentitis, is an uncommon disease of episodic immune dysregulation that usually begins in early childhood.
Dennis J. Baumgardner
doaj   +1 more source

Molecular epidemiology of Coxiella burnetii from ruminants in Q fever outbreak, the Netherlands. [PDF]

, 2011
Q fever is a zoonosis caused by the bacterium Coxiella burnetii. One of the largest reported outbreaks of Q fever in humans occurred in the Netherlands starting in 2007; epidemiologic investigations identified small ruminants as the source.
Rob Buijs, Willemsen, P.T.J., Albert G. de Boer, Wouda, W., Willem Wouda, Corné H.W. Klaassen, Daan Dercksen, Spek, A.N., Van der, Van den Brom, R., Robin C. Ruuls, Ruuls, R.C., Fred G. van Zijderveld, Nabuurs-Fransen, M.H., Tilburg, J.H.H.C., Dercksen, D., Klaassen, C.H.W., Buijs, R., Vellema, P., Marrigje H. Nabuurs-Franssen, Arco N. van der Spek, Spierenburg, M., René van den Brom, Peter Th.J. Willemsen, Roest, H.I.J., Van der Spek, A.N., Brom, R., Van den, Jeroen J.H.C. Tilburg, Piet Vellema, Hendrik I.J. Roest, Marcel A.H. Spierenburg   +29 more
core   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Transitional care management in patients with auto-inflammatory diseases: experience of cooperation of a paediatric and adult centre

Journal of Transition Medicine, 2022
Auto-inflammatory Diseases (AIDs) are a group of diseases with a strong genetic component, inducing an inappropriate activation of innate immunity. The patients with pediatric onset will face the transitional care (TC) from a pediatrician to an adult ...
Soscia Francesca, Sicignano Ludovico Luca, Verrecchia Elena, Ardenti Morini Francesca, Massaro Maria Grazia, Civitelli Fortunata Sabrina, Ferrari Federica, Rigante Donato, Cortis Elisabetta, Manna Raffaele   +9 more
doaj   +1 more source

A large pericardial effusion and bilateral pleural effusions as the initial manifestations of Familial Mediterranean Fever [PDF]

, 2015
Familial Mediterranean Fever (FMF) is a condition characterized by recurrent febrile poly-serositis. Typical presentations of the disease include episodes of fever, abdominal pain and joint pains. Chest pain is a less common presentation.
Mallia, Carmel, Mifsud, Simon, Cassar Demarco, Daniela, Coleiro, Bernard, Schembri, Emma Louise   +4 more
core  

Locally periodic unfolding method and two-scale convergence on surfaces of locally periodic microstructures [PDF]

, 2015
In this paper we generalize the periodic unfolding method and the notion of two-scale convergence on surfaces of periodic microstructures to locally-periodic situations.
Ptashnyk, Mariya, Ptashnyk, Mariya; id_orcid, Mariya Ptashnyk   +2 more
core   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Computational Methods for Periodic Systems - An Overview [PDF]

, 2001
We present an up-to-date survey of numerical methods for the analysis and design of linear discrete-time periodic systems. The basic tool is the periodic Schur form and its variants, for which a certain form of numerical stability can be ...
IFAC Workshop on Periodic Control Systems (PSYCO 2001), Dooren, Paul Van, Varga, Andras, Van Dooren, Paul   +3 more
core  

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi, Katharine Lee, Kerry C. Nix, Miguel Menchaca, Xiwei Shé, Lorelei Santa Maria, Wei Wu, Zihuai He, Fiona M. Baumer   +8 more
wiley   +1 more source