Results 81 to 90 of about 42,983 (297)

The effect of neutrophil-lymphocyte ratio and thrombocyte index on inflammation in patients with periodic fever, aphthous stomatitis, pharyngitis, and adenitis syndrome

open access: yesIndian Journal of Rheumatology, 2020
Background: The periodic fever, aphthous stomatitis, pharyngitis, and adenitis (PFAPA) syndrome is the most common periodic fever syndrome in childhood. Its pathogenesis and etiology remain unknown.
Vildan Gungorer   +3 more
doaj   +1 more source

NIBV Induces Incomplete Autophagy via AMPK‐TFEB, Causing Kidney Injury in Chicks

open access: yesAdvanced Science, EarlyView.
This study reveals that NIBV can inhibit the nuclear translocation of TFEB by suppressing the expression of AMPK, leading to the blockade of autophagolysosomal functions, in turn increasing NIBV replication and triggering severe kidney injury in chicks.
Cheng Huang   +10 more
wiley   +1 more source

TRAPS: An Autosomal Dominant Autoinflammatory Syndrome

open access: yesEurasian Journal of Medicine, 2019
Hereditary periodic fever syndromes are genetic autoinflammatory disorders characterized by recurrent attacks of fever and inflammation. These diseases include familial Mediterranean fever (FMF), Tumor necrosis factor receptor-associated periodic ...
Saliha Karatay, Meltem Alkan Melikoğlu
doaj  

Cyclical Fevers in a 4-year-old Boy with IgA Deficiency

open access: yesReports, 2019
While immunodeficiencies, such as (Immunoglobulin A) IgA deficiency, may predispose pediatric patients to respiratory illnesses, they are also associated with autoinflammatory conditions.
Joshua Y.C. Yang
doaj   +1 more source

The Genetic Basis for Periodic Fever [PDF]

open access: yesThe American Journal of Human Genetics, 1999
The periodic-fever syndromes are a genetically heterogeneous group of inflammatory disorders characterized by recurrent fever, abdominal pain, and polyserositis. The clinically distinct entities of familial Mediterranean fever (FMF; MIM 249100) and hyperimmunoglobulinemia D with periodic fever (MIM 260920) are autosomal recessive and genetically ...
openaire   +2 more sources

PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe

open access: yesAdvanced Science, EarlyView.
This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao   +14 more
wiley   +1 more source

Spread and Control of Rift Valley Fever virus after accidental introduction in the Netherlands: a modelling study.

open access: yes, 2011
Rift Valley Fever (RVF) is a zoonotic vector-borne infection and causes a potentially severe disease in both humans and young animals. The Ministry of Economic Affairs, Agriculture and Innovation (EL&I) is interested in the risk of an outbreak of Rift ...
Fischer, E.A.J.   +6 more
core  

The role of Mediterranean fever gene variants in patients with periodic fever, aphthous stomatitis, pharyngitis, and adenitis syndrome

open access: yes, 2021
© 2020, Springer-Verlag GmbH Germany, part of Springer Nature.This study was conducted to investigate the relationship between clinic features and Mediterranean fever gene (MEFV) variants in patients with periodic fever, aphthous stomatitis, pharyngitis,
Kasapcopur, Ozgur   +8 more
core   +1 more source

Tetrastigma Hemsleyanum Polysaccharide Suppresses Triple‐Negative Breast Cancer by Disrupting the Hippo‐YAP/TEAD4‐PDIA4 Axis and Endoplasmic Reticulum Stress Adaptation

open access: yesAdvanced Science, EarlyView.
ABSTRACT Triple‐negative breast cancer (TNBC) exhibits addiction to chronic endoplasmic reticulum (ER) stress, which sustains an aggressive metastatic phenotype through activation of the unfolded protein response (UPR). Here, we identify a previously unrecognized “ER‐stress addiction” axis in which the Hippo pathway effector TEAD4 directly ...
Yini Shang   +9 more
wiley   +1 more source

Periodic Fever Syndromes

open access: yes, 2007
When common infectious agents and other causes of fever such as neoplastic and rheumatologic diseases, immune deficiencies, various endocrinologic and metabolic disorders are differentiated, periodic fever syndromes must be brought in mind in recurrent ...
Barlan, Işıl Berat   +4 more
core  

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