Results 121 to 130 of about 241,774 (311)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
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Periodic-by-Nilpotent Linear Groups
Rendiconti del Seminario Matematico della Università di Padova, 2010 Let G be a linear group of (finite) degree n and characteristic p ≥ 0 .
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Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
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On Morse–Smale diffeomorphisms on simply connected manifolds
Partial Differential Equations in Applied MathematicsWe study relations between a structure of non-wandering set of a Morse–Smale diffeomorphism f and its carrying closed manifold Mn. We prove that if f has no any saddle periodic points with one-dimensional unstable manifolds, and for any periodic point σ ...
E.Y. Gurevich, I.A. Saraev
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Armaghane Danesh Bimonthly Journal, 2021 Background & aim: Adipose tissue is not just a source of excess energy storage, but an endocrine organ that regulates biological functions by endocrine role by releasing adipokines that act like real hormones. The aim of this study was to investigate the
B Hasanvand +4 more
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Almost Periodic Functions in Groups
Hiroshima Mathematical Journal, 1941 Not ...
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
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Stability and Hopf bifurcation periodic orbits in delay coupled Lotka-Volterra ring system
Open Mathematics, 2019 In this paper, we consider a class of delay coupled Lotka-Volterra ring systems. Based on the symmetric bifurcation theory of delay differential equations and representation theory of standard dihedral groups, properties of phase locked periodic ...
Su Rina, Zhang Chunrui
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Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
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On Direct Products of Dihedral Groups in Locally Finite Groups
Известия Иркутского государственного университета: Серия "Математика"When studying infinite groups, as a rule, some finiteness conditions are imposed. For example, they require that the group be periodic, a Shunkov group, a Frobenius group, or a locally finite group.
I. A. Timofeenko, A.A. Shlepkin
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