Results 61 to 70 of about 9,926,750 (356)

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

$M$-periodic problem of order $2k$

open access: yesTopological Methods in Nonlinear Analysis, 1998
The author gives sufficient conditions for the existence of solutions to some general matrix-periodic problems of higher even order, which have a variational structure. A key tool in the proofs is a generalization of the Du Bois-Reymond lemma for periodic functions of order one, which was proved by the author in a previous work [Gȩba, Kazimierz (ed ...
openaire   +4 more sources

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

On lattice ordered periodic semigroups [PDF]

open access: yesCzechoslovak Mathematical Journal, 1993
The purpose of this note is to give some algebraic properties of lattice- ordered periodic semigroups and particularly in the finite case. The main results. Classes of the following equivalence relation \(\mathcal F\) are called spindles and will be denoted \(F_ e\), where \(e\) is the idempotent of this class: \(a\equiv b{\mathcal F}\Leftrightarrow e ...
openaire   +2 more sources

Bounded and periodic solutions to the linear first-order difference equation on the integer domain

open access: yes, 2017
The existence of bounded solutions to the linear first-order difference equation on the set of all integers is studied. Some sufficient conditions for the existence of solutions converging to zero when n→−∞$n\to -\infty$, as well as when n→+∞$n\to+\infty$
S. Stević
semanticscholar   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

The period functionsʼ higher order derivatives

open access: yesJournal of Differential Equations, 2012
We prove a formula for the $n$-th derivative of the period function $T$ in a period annulus of a planar differential system. For $n = 1$, we obtain Freire, Gasull and Guillamon formula for the period's first derivative \cite{FGG}. We apply such a result to hamiltonian systems with separable variables and other systems.
openaire   +3 more sources

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