Results 131 to 140 of about 11,597,312 (305)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Effect of Frequency Aerobic Exercise on Expression of Bcl-2 and Bax Gene in Mice With Myocardial Infarction

open access: yesArmaghane Danesh Bimonthly Journal, 2018
  Background and Aim: Myocardial infarction (MI) is a permanent and irreversible cell death and death of the myocardium. Physical training reduces cardiac muscle apoptosis, but its molecular process is still unknown in response to activity and also ...
M Ghahremani   +3 more
doaj  

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Resonant nonlinear periodic problems with the scalar p-Laplacian and a nonsmooth potential [PDF]

open access: yes, 2006
We study periodic problems driven by the scalar p-Laplacian with a nonsmooth potential. Using the nonsmooth critical point theory for locally Lipsctiz functions,we prove two existence theorems under conditions of resonance at infinity with respect to ...
Staicu, Vasile   +6 more
core  

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Water regulation: the periodic review [PDF]

open access: yes
Since the privatisation of the water industry in 1989, issues relating to the pricing of water, charging structures and the conduct of the water regulators have rarely been out of public attention.
Dieter Helm, Najma Rajah
core  

Strongly stable algorithm for computing periodic system zeros [PDF]

open access: yes, 2003
We propose a computationally efficient and numerically reliable algorithm to compute the finite zeros of a linear discrete-time periodic system. The zeros are defined in terms of the transfer-function matrix corresponding to an equivalent lifted time ...
Varga, Andras
core  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Computation of minimal periodic realizations of transfer-function matrices [PDF]

open access: yes, 2003
We present a numerical approach to compute a minimal periodic state-space realization of a transfer-function matrix corresponding to a lifted state-space representation.
Varga, A., Varga, Andras
core  

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

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