Results 91 to 100 of about 8,371,508 (357)
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Dynamical behaviors of a two-competitive metapopulation system with impulsive control
Advances in Difference Equations, 2017 In this paper, we study the dynamical behaviors of a two-competitive metapopulation system with impulsive control and focus on the stable coexistence of the superior and inferior species.
Shasha Tian, Yepeng Xing, Tao Ma
doaj +1 more source
Molecular Oncology, EarlyView.Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser +14 more
wiley +1 more source
On the solutions of a second order difference equation [PDF]
Mathematica Moravica, 2017 In this paper, we discuss the global behavior of all solutions of the difference equation Xn+1 = XnXn-1 axn + bxn-1, n € N0, where a; b are real numbers and the initial conditions X-1, X0 are real numbers.
Abo-Zeid R.
doaj
Journal of Applied Mathematics, 2014 A mathematical model on schistosomiasis governed by periodic differential equations with a time delay was studied. By discussing boundedness of the solutions of this model and construction of a monotonic sequence, the existence of positive periodic ...
Lin Li, Zhicheng Liu
doaj +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
On the existence of periodic solution of perturbed generalized Li\'enard equations
, 2006 Under conditions of Levinson-Smith type, we prove the existence of a $\tau$-periodic solution for the perturbed generalized Li\'enard equation u''+\phi(u,u')u'+\psi(u)=\epsilon\omega(\frac{t}{\tau},u,u') with periodic forcing term.
Boussaada, Islam, Chouikha, A. Raouf
core +1 more source
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Existence of Periodic Solution for a Nonlinear Fractional Differential Equation
, 2009 We study the existence of solutions for a class of fractional differential equations. Due to the singularity of the possible solutions, we introduce a new and proper concept of periodic boundary value conditions. We present Green's function and give some
M. Belmekki +2 more
semanticscholar +1 more source
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source