Results 101 to 110 of about 1,003,535 (311)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
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Periodic solution for ϕ-Laplacian neutral differential equation
Open Mathematics, 2019 This paper is devoted to the existence of a periodic solution for ϕ-Laplacian neutral differential equation as follows (ϕ(x(t)−cx(t−τ))′)′=f(t,x(t),x′(t)).$$\begin{array}{} (\phi(x(t)-cx(t-\tau))')'=f(t,x(t),x'(t)). \end{array}$$
Yao Shaowen, Cheng Zhibo
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Fundamental Solutions for Periodic Media [PDF]
Advances in Mathematical Physics, 2014 Necessity for the periodic fundamental solutions arises when the periodic boundary value problems should be analyzed. The latter are naturally related to problems of finding the homogenized properties of the dispersed composites, porous media, and media with uniformly distributed microcracks or dislocations.
openaire +3 more sources
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
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β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Positive periodic solutions for second-order neutral differential equations with functional delay
Electronic Journal of Differential Equations, 2012 We use Krasnoselskii's fixed point theorem to prove the existence of positive periodic solutions of the second-order nonlinear neutral differential equation $$ frac{d^2}{dt^2}x(t)+p(t)frac{d}{dt}x(t)+q(t)x(t) =cfrac{d}{dt}x(t-au(t))+f(t,h(x(t)),g(x ...
Ernest Yankson
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Periodic Systems Dependent on Parameters
Journal of Inequalities and Applications, 2010 This paper is concerned with a periodic system dependent on parameter. We study differentiability with respect to parameters of the periodic solution of the system. Applying a fixed point theorem and the results regarding parameters for C0-semigroups, we
Min He
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Three periodic solutions for an ordinary differential inclusion with two parameters [PDF]
, 2011 Antonio Iannizzotto
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Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Advances in Difference Equations, 2009 The existence of periodic, almost periodic, and asymptotically almost periodic of periodic and almost periodic of abstract retarded functional difference equations in phase spaces is obtained by using stability properties of a bounded solution.
Claudio Vidal
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