Results 121 to 130 of about 128,153 (317)

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Investigating the Potential of LS 5039 as a Triple System Using Fermi-LAT Data

The Astrophysical Journal
LS 5039 is one of a handful of γ -ray binary systems in the milky Way, comprising a pulsar and a massive O-type companion star with an orbital period of 3.9 days.
Lujun Zeng, Mengqing Zhang, Chongyang Ren, Pengfei Zhang, Jingzhi Yan   +4 more
doaj   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

A New Puzzling Periodic Signal in GeV Energies of the γ-Ray Binary LS I+61°303

The Astrophysical Journal
LS I+61°303 is a high-mass X-ray binary system comprising a massive Be star and a rapidly rotating neutron star. Its spectral energy distribution across multiwavelengths categorizes it as a γ -ray binary system. In our analysis of LS I+61°303 using Fermi
Pengfei Zhang
doaj   +1 more source

PROGRAM WWZ: WAVELET ANALYSIS OF ASTRONOMICAL SIGNALS WITH IRREGULARLY SPACED ARGUMENTS

Odessa Astronomical Publications, 2013
A program WWZ is introduced, which realizes the wavelet analysis using an improved modification of the algorithm of the Morlet wavelet for a general case of irregularly spaced data, which is typical for the databases available in virtual observatories ...
I. L. Andronov, A. V. Naumova
doaj   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Establishing Baselines for Six Short-period δ Scuti Variables

The Astronomical Journal
As part of our variable star follow-up program, we have examined a number of stars from the Asteroid Terrestrial-impact Last Alert System (ATLAS) survey. Using a combination of our own data, ATLAS data, and other archival data, we confirmed the published
Christiana Z. Suggs, Eric G. Hintz, Denise C. Stephens   +2 more
doaj   +1 more source

Analysing periodic amplitude changes in RR Lyrae and other types of variable stars [PDF]

, 2008
E. Guggenberger, K. Kolenberg, M. Breger
openalex   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Near Continuous Photometry with the Whole Earth Telescope (WET)

Open Astronomy, 2003
The Whole Earth Telescope (WET) saw first light in 1988. It was invented by scientists from the Astronomy Department, University of Texas at Austin.
Solheim J. E.
doaj   +1 more source