Results 121 to 130 of about 126,616 (274)

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

open access: yesFEBS Open Bio, EarlyView.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti   +8 more
wiley   +1 more source

The Optical Photometric Variability of Herbig Ae/Be Stars from TESS

open access: yesThe Astrophysical Journal
We have carried out a photometric time domain study of 188 intermediate-mass young stars observed in Full Frame Image mode with the Transiting Exoplanet Survey Satellite (TESS) satellite over the first 3.3 yr of its mission. The majority of these targets
Ann Marie Cody   +3 more
doaj   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Heartbeat Stars Recognition Based on Recurrent Neural Networks: Method and Validation

open access: yesThe Astronomical Journal
Since the variety of their light curve morphologies, the vast majority of the known heartbeat stars (HBSs) have been discovered by manual inspection. Machine learning, which has already been successfully applied to the classification of variable stars ...
Min-Yu Li   +9 more
doaj   +1 more source

Production of antibacterial compounds by a Steely hybrid polyketide synthase in Dictyostelium

open access: yesFEBS Open Bio, EarlyView.
By selecting appropriate production species under optimised culture conditions, new chlorinated dibenzofuran compounds, which previously could not be analysed in sufficient quantities, were identified from cellular slime mould fruiting bodies. The strong antibacterial activity exhibited by these compounds suggests a link to the ecological function of ...
Tomoaki R. Yamashita   +3 more
wiley   +1 more source

A Plasma Torus around a Young Low-mass Star

open access: yesThe Astrophysical Journal Letters
A small fraction of red dwarfs younger than ∼100 million years show structured, periodic optical light curves suggestive of transiting opaque material that corotates with the star. However, the composition, origin, and even the existence of this material
Luke G. Bouma, Moira M. Jardine
doaj   +1 more source

Searching for Anomalies in the ZTF Catalog of Periodic Variable Stars

open access: green, 2021
H. S. Chan   +6 more
openalex   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

open access: yesFEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel   +9 more
wiley   +1 more source

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