Results 121 to 130 of about 123,975 (308)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Evaluation at Half Periods of Weierstrass' Elliptic Function With Rectangular Primitive Period-Parallelogram [PDF]
Mathematics of Computation, 1960 (2) Wl + 2 + 2?3 = ?In this note, these three functions will be evaluated, also to 16D, for the case of rhombic primitive period-parallelogram. Two methods of evaluation are given. One is similar to that described previously [1] and the other is in terms of Jacobian Theta functions.
openaire +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Evaluation of and period polynomial relations
Forum of Mathematics, SigmaAbstract In studying the depth filtration on multiple zeta values, difficulties quickly arise due to a disparity between it and the coradical filtration [9]. In particular, there are additional relations in the depth graded algebra coming from period polynomials of cusp forms for $\operatorname {\mathrm {SL}}_2({\mathbb {Z}})$
Steven Charlton, Adam Keilthy
openaire +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Ciência da Informação, 1993 Avalia quantitativamente a coleção de periódicos doados à Biblioteca da Faculdade de Economia e Administração e Instituto de Economia (FEAIEI) da Universidade Federal do Rio de Janeiro (UFRJ), pela freqüência de uso por meio de empréstimos domiciliares e
Maria Aparecida de Andrade Teixeira +1 more
doaj
Introducing Electronic Information Services to First-Year Composition Students: Pedagogical and Practical Concerns [PDF]
, 1994 More and more of the college and university library\u27s resources are becoming computerized. As first year students enter the library, they are often confronted with an overwhelming array of computer terminals and workstations.
Mandernack, Scott
core +1 more source
The TIANSHAN Radio Experiment for Neutrino Detection
, 2010 An antenna array devoted to the autonomous radio-detection of high energy cosmic rays is being deployed on the site of the 21 cm array radio telescope in XinJiang, China.
Abraham +46 more
core +5 more sources
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source