Results 51 to 60 of about 34,293 (348)

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Evaluation of Manuscript Preference of Sci-Tech Periodicals: Structural Topic Models of Computer Engineering Related Publications in China [PDF]

, 2022
Xiang Li
openalex   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Adequacy of pharmacological information provided in pharmaceutical drug advertisements in African medical journals.

Pharmacy Practice, 2009
Pharmaceutical advertisement of drugs is a means of advocating drug use and their selling but not a substitute for drug formulary to guide physicians in safe prescribing.
Oshikoya KA, Senbanjo IO, Soipe A
doaj  

Analysis of Publishing Information and Popular Topics of Tax Accounting Periodical Issues in Indonesia [PDF]

, 2023
Khusnul Khotimah, Heri Widodo, Duwi Rahayu, Eny Maryati   +3 more
openalex   +1 more source

Use of Citation Data for Periodicals Control in Libraries: A Response to Broadus

, 1985
obert Broadus' paper on the use of Journal Citation Reports (JCR) for reducing periodical subscriptions is interesting, but like other papers on this topic it misses a crucial practical issue.
M. Line
semanticscholar   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Emerging concepts in high-impact publishing: insights from the First Brazilian Colloquium on High Impact Research and Publishing

Annali dell'Istituto Superiore di Sanità
Reports of scientific research are published by selective journals only when they meet stringent criteria, first and foremost of which are the quality and importance of the research.
Valerie Matarese
doaj   +1 more source

The Assessment of Iranian Systematic Review Articles in Biomedical Sciences Based on the Scientometrics Methods

مدیریت اطلاعات سلامت, 2019
Introduction: Studying the growth of scientific outputs in different subject areas can be one of the foundations of scientific policymaking in that field.
Sornaz Shadi, Saeid Asadi, Hamzeali Nourmohammadi   +2 more
doaj   +1 more source