Results 61 to 70 of about 34,872 (324)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
LAUNCHING UKRAINIAN COUNCIL OF SCIENCE EDITORS AND EDUCATING REGIONAL JOURNAL EDITORS
Праці Наукового товариства імені Шевченка. Медичні науки, 2020 Global editorial associations have accumulated knowledge and resources that could be helpful for emerging editors groups and societies. Increasing awareness of and enforcing the available editorial recommendations is essential for improving the quality ...
Olena Zimba +2 more
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Periodicals of the Volga region during the First World War: topics of publications, district and provincial press [PDF]
, 2021 Ekaterina Yu. Semenova
openalex +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Southwest Respiratory and Critical Care Chronicles, 2015 Clarity is the most significant aspect of medical writing. This article explains the importance of clarity and offers practical advice for writing clearly at the language and sentence levels.
Kristin Messuri
doaj
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Southwest Respiratory and Critical Care Chronicles, 2016 Choosing precise, vivid verbs improves the clarity and enhances the style of medical writing. Ideally, writers should use precise, vivid verbs in medical writing and other genres.
Kristin Messuri
doaj
Analysis of ten years of publishing in Pharmacy Practice
Pharmacy Practice, 2016 Objective: The aim of this study is to characterize the patterns and trends in the editorial process and features of the first decade of Pharmacy Practice, with the final goal of initiating a benchmarking process to enhance the quality of the journal ...
Mendes AE +2 more
doaj +1 more source