Results 71 to 80 of about 386,403 (270)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Almost periodic functions in quantum calculus

Electronic Journal of Differential Equations, 2018
In this article, we introduce the concepts of Bochner and Bohr almost periodic functions in quantum calculus and show that both concepts are equivalent.
Martin Bohner, Jaqueline G. Mesquita
doaj  

Location Analytics of Routine Occurrences (LARO) to Identify Locations with Regularly Occurring Events with a Case Study on Traffic Accidents

Information
Conventional spatiotemporal methods take frequentist or density-based approaches to map event clusters over time. While these methods discern hotspots of varying continuity in space and time, their findings overlook locations of routine occurrences where
Yanan Wu, Yalin Yang, May Yuan
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Study on the Water Volume of Erhai Lake in Yunnan Plateau

Renmin Zhujiang, 2021
Based on the monitoring results of hydrological factors such as measured discharge,precipitation,evaporation and outflow in the Erhai Lake Basin from 1956 to 2018,this paper calculates the natural water volume of the Erhai Lake by using two related ...
LI Hongyan
doaj  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Trend in total terrestrial water storage at the European Russia detected based on GRACE DATA

Бюллетень Почвенного института им. В.В. Докучаева, 2016
The data obtained by GRACE satellite allowed comprehensively analyzing the dynamics of total terrestrial water storage within the period from 2003 to 2012 at the territory of European Russia.
I. Yu. Savin, M. L. Markov, S. V. Ovechkin, V. A. Isaev   +3 more
doaj   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Experience in Teaching Mendeleev’s Periodic Law at National Research University

Высшее образование в России, 2019
The article discusses the questions concerning the presentation of the essence of the D.I. Mendeleev’s Periodic Law in the modern educational process in the framework of general educational and special chemical disciplines “General Chemistry”, “Inorganic
O. V. Mikhailov
doaj   +1 more source