Results 21 to 30 of about 269,676 (192)

Distinct phases of adult microglia proliferation: a Myc-mediated early phase and a Tnfaip3-mediated late phase

Cell Discovery, 2022
Microgliosis is a hallmark of many neurological diseases, including Alzheimer’s disease, stroke, seizure, traumatic brain and spinal cord injuries, and peripheral and optic nerve injuries.
Wulin Tan, Po-Yi Paul Su, Jacqueline Leff, Xiang Gao, Jiao Chen, Andrew K. Guan, Gokul Kalyanasundaram, Averil Ma, Zhonghui Guan   +8 more
doaj   +1 more source

Effects of pre-emptive pregabalin and multimodal anesthesia on postoperative opioid requirements in patients undergoing robot-assisted laparoscopic prostatectomy

BMC Urology, 2021
Background Previous findings indicate that pre-emptive pregabalin as part of multimodal anesthesia reduces opioid requirements compared to conventional anesthesia in patients undergoing robot-assisted laparoscopic prostatectomy (RALP).
K. Sisa, S. Huoponen, O. Ettala, H. Antila, T. I. Saari, P. Uusalo   +5 more
doaj   +1 more source

Renal resistive index is associated with acute kidney injury in COVID-19 patients treated in the intensive care unit

The Ultrasound Journal, 2021
Background Renal resistive index (RRI) is a promising tool for the assessment of acute kidney injury (AKI) in critically ill patients in general, but its role and association to AKI among patients with Coronavirus disease 2019 (COVID-19) is not known ...
Mårten Renberg, Olof Jonmarker, Naima Kilhamn, Claire Rimes-Stigare, Max Bell, Daniel Hertzberg   +5 more
doaj   +1 more source

Obstructive sleep apnea syndrome and perioperative complications: a systematic review of the literature. [PDF]

, 2012
Obstructive sleep apnea syndrome (OSAS) is a common sleep related breathing disorder. Its prevalence is estimated to be between 2% and 25% in the general population.
Doghramji, MD, Karl, Grewal, MD, Ritu G., Vasu, MD, MS, Tajender S.   +2 more
core   +2 more sources

Nationwide case–control study of risk factors and outcomes for community-acquired sepsis

Scientific Reports, 2021
Sepsis is the main cause of death in the intensive care units (ICU) and increasing incidences of ICU admissions for sepsis are reported. Identification of patients at risk for sepsis and poor outcome is therefore of outmost importance.
Ann-Charlotte Lindström, Mikael Eriksson, Johan Mårtensson, Anders Oldner, Emma Larsson   +4 more
doaj   +1 more source

Glucocorticoid-endocannabinoid interaction in cardiac surgical patients: relationship to early cognitive dysfunction and late depression [PDF]

, 2012
Background: Endocannabinoids (ECs) are rapidly acting immune-modulatory lipid-signaling molecules that are important for adaptation to stressful and aversive situations. They are known to interact with glucocorticoids and other stress-responsive systems.
Beiras-Fernandez, Andres, Campolongo, Patrizia, Giehl, Markus, Hauer, Daniela, Kilger, Erich, Schelling, Gustav, Schopp, Mirjam, Strewe, Claudia, Toth, Roland, Weis, Florian   +9 more
core   +1 more source

N -Oleoyl dopamine induces IL-10 via central nervous system TRPV1 and improves endotoxemia and sepsis outcomes

Journal of Neuroinflammation, 2022
Background The transient receptor potential vanilloid 1 (TRPV1) participates in thermosensation and inflammatory pain, but its immunomodulatory mechanisms remain enigmatic.
Jérémie Joffre, Erika Wong, Samira Lawton, Elliot Lloyd, Nina Nguyen, Fengyun Xu, Cristina Sempio, Lester Kobzik, Ivana Zlatanova, Mark Schumacher, Jost Klawitter, Hua Su, Katalin Rabl, Kevin Wilhelmsen, Che-Chung Yeh, Judith Hellman   +15 more
doaj   +1 more source

Clinical review: Can we predict which patients are at risk of complications following surgery? [PDF]

, 2013
There are a vast number of operations carried out every year, with a small proportion of patients being at highest risk of mortality and morbidity. There has been considerable work to try and identify these high-risk patients.
Hamilton, M, Shah, N
core   +1 more source

Perioperative Pleural Drainage in Liver Transplantation: A Retrospective Analysis from a High-Volume Liver Transplant Center [PDF]

, 2020
BACKGROUND Pleural effusions represent a common complication after liver transplantation (LT) and chest drain (CD) placement is frequently necessary. MATERIAL AND METHODS In this retrospective cohort study, adult LT recipients between 2009 and 2016 were ...
Aigner, Felix, Brandl, Andreas, Dargie, Richard, Dziodzio, Tomasz, Eurich, Dennis, Jara, Maximilian, Kotsch, Katja, Pratschke, Johann, Ritschl, Paul Viktor, Sauer, Igor M., Schmelzle, Moritz, Sponholz, Felix, Wiering, Leke, Öllinger, Robert   +13 more
core   +1 more source

Perioperative myocardial injury is associated with increased postoperative non-cardiac complications in patients undergoing vascular surgery: a post hoc analysis of a randomised clinical pilot trial

Perioperative Medicine, 2023
Background Elevated cardiac biomarkers, such as high-sensitivity cardiac Troponin T and N-terminal pro-B-type natriuretic peptide improve the prediction of major adverse cardiac events.
A. Valadkhani, A. Gupta, M. Bell
doaj   +1 more source