Results 21 to 30 of about 162,977 (292)

Distinct phases of adult microglia proliferation: a Myc-mediated early phase and a Tnfaip3-mediated late phase

Cell Discovery, 2022
Microgliosis is a hallmark of many neurological diseases, including Alzheimer’s disease, stroke, seizure, traumatic brain and spinal cord injuries, and peripheral and optic nerve injuries.
Wulin Tan, Po-Yi Paul Su, Jacqueline Leff, Xiang Gao, Jiao Chen, Andrew K. Guan, Gokul Kalyanasundaram, Averil Ma, Zhonghui Guan   +8 more
doaj   +1 more source

Renal resistive index is associated with acute kidney injury in COVID-19 patients treated in the intensive care unit

The Ultrasound Journal, 2021
Background Renal resistive index (RRI) is a promising tool for the assessment of acute kidney injury (AKI) in critically ill patients in general, but its role and association to AKI among patients with Coronavirus disease 2019 (COVID-19) is not known ...
Mårten Renberg, Olof Jonmarker, Naima Kilhamn, Claire Rimes-Stigare, Max Bell, Daniel Hertzberg   +5 more
doaj   +1 more source

Effects of pre-emptive pregabalin and multimodal anesthesia on postoperative opioid requirements in patients undergoing robot-assisted laparoscopic prostatectomy

BMC Urology, 2021
Background Previous findings indicate that pre-emptive pregabalin as part of multimodal anesthesia reduces opioid requirements compared to conventional anesthesia in patients undergoing robot-assisted laparoscopic prostatectomy (RALP).
K. Sisa, S. Huoponen, O. Ettala, H. Antila, T. I. Saari, P. Uusalo   +5 more
doaj   +1 more source

Nationwide case–control study of risk factors and outcomes for community-acquired sepsis

Scientific Reports, 2021
Sepsis is the main cause of death in the intensive care units (ICU) and increasing incidences of ICU admissions for sepsis are reported. Identification of patients at risk for sepsis and poor outcome is therefore of outmost importance.
Ann-Charlotte Lindström, Mikael Eriksson, Johan Mårtensson, Anders Oldner, Emma Larsson   +4 more
doaj   +1 more source

Perioperative myocardial injury is associated with increased postoperative non-cardiac complications in patients undergoing vascular surgery: a post hoc analysis of a randomised clinical pilot trial

Perioperative Medicine, 2023
Background Elevated cardiac biomarkers, such as high-sensitivity cardiac Troponin T and N-terminal pro-B-type natriuretic peptide improve the prediction of major adverse cardiac events.
A. Valadkhani, A. Gupta, M. Bell
doaj   +1 more source

N -Oleoyl dopamine induces IL-10 via central nervous system TRPV1 and improves endotoxemia and sepsis outcomes

Journal of Neuroinflammation, 2022
Background The transient receptor potential vanilloid 1 (TRPV1) participates in thermosensation and inflammatory pain, but its immunomodulatory mechanisms remain enigmatic.
Jérémie Joffre, Erika Wong, Samira Lawton, Elliot Lloyd, Nina Nguyen, Fengyun Xu, Cristina Sempio, Lester Kobzik, Ivana Zlatanova, Mark Schumacher, Jost Klawitter, Hua Su, Katalin Rabl, Kevin Wilhelmsen, Che-Chung Yeh, Judith Hellman   +15 more
doaj   +1 more source

Impact of gender on post- traumatic intensive care and outcomes

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 2019
Background Several reports indicate gender disparities in health care provision. There is a well-documented male patient dominance in intensive care unit (ICU) admittance.
Emma Larsson, Ann-Charlotte Lindström, Mikael Eriksson, Anders Oldner   +3 more
doaj   +1 more source

Lack of impact of nil-per-os (NPO) time on goal-directed fluid delivery in first case versus afternoon case starts: a retrospective cohort study

BMC Anesthesiology, 2019
Background Goal Directed Fluid Therapy (GDFT) represents an objective fluid replacement algorithm. The effect of provider variability remains a confounder.
R. Ryan Field, Tuan Mai, Samouel Hanna, Brian Harrington, Michael-David Calderon, Joseph Rinehart   +5 more
doaj   +1 more source

Predictors of weaning failure in case of VA ECMO implantation

Scientific Reports, 2022
The use of veno-arterial extracorporeal membrane oxygenation (VA ECMO) for the treatment of refractory cardiogenic shock has increased significantly. Nevertheless, early weaning may be advisable to reduce the potential for severe complications.
Axelle Cusanno, Nadia Aissaoui, Vincent Minville, Jean Porterie, Caroline Biendel, Kim Volle, Laure Crognier, Jean-Marie Conil, Clément Delmas   +8 more
doaj   +1 more source

Left atrial contraction strain and controlled preload alterations, a study in healthy individuals

Cardiovascular Ultrasound, 2022
Background In order to assess left atrial contractile function in disturbed circulatory conditions, it is necessary to have a clear understanding of how it behaves in a normal resting state with changes in loading conditions.
Peter Gottfridsson, Roman A’Roch, Per Lindqvist, Lucy Law, Tomi Myberg, Magnus Hultin, Alexander A’Roch, Michael Haney   +7 more
doaj   +1 more source