Results 1 to 10 of about 2,070,612 (310)

3D Printed Conductive Multiscale Nerve Guidance Conduit with Hierarchical Fibers for Peripheral Nerve Regeneration

Advancement of science, 2023
Nerve guidance conduits (NGCs) have become a promising alternative for peripheral nerve regeneration; however, the outcome of nerve regeneration and functional recovery is greatly affected by the physical, chemical, and electrical properties of NGCs.
Yongcong Fang, Chengjin Wang, Zibo Liu, Jeonghoon Ko, Li Chen, Ting Zhang, Zhuo Xiong, Lei Zhang, Wei Sun   +8 more
semanticscholar   +1 more source

3D Printed Personalized Nerve Guide Conduits for Precision Repair of Peripheral Nerve Defects

Advancement of science, 2022
The treatment of peripheral nerve defects has always been one of the most challenging clinical practices in neurosurgery. Currently, nerve autograft is the preferred treatment modality for peripheral nerve defects, while the therapy is constantly plagued
Kai Liu, Lesan Yan, Ruo-nan Li, Zhiming Song, Jianxun Ding, Bin Liu, Xuesi Chen   +6 more
semanticscholar   +1 more source

Single-cell RNA sequencing reveals time- and sex-specific responses of mouse spinal cord microglia to peripheral nerve injury and links ApoE to chronic pain

Nature Communications, 2022
Activation of microglia in the spinal cord following peripheral nerve injury is critical for the development of long-lasting pain hypersensitivity. However, it remains unclear whether distinct microglia subpopulations or states contribute to different ...
Shannon N Tansley, Sonali Uttam, Alba Ureña Guzmán, Moein Yaqubi, Alain S Pacis, M. Parisien, Haley Deamond, Calvin Wong, O. Rabau, Nicole Brown, L. Haglund, J. Ouellet, Carlo Santaguida, A. Ribeiro-da-Silva, Soroush Tahmasebi, M. Prager-Khoutorsky, J. Ragoussis, Ji Zhang, M. Salter, L. Diatchenko, Luke M. Healy, J. Mogil, A. Khoutorsky   +22 more
semanticscholar   +1 more source

Magnesium‐Encapsulated Injectable Hydrogel and 3D‐Engineered Polycaprolactone Conduit Facilitate Peripheral Nerve Regeneration

Advancement of science, 2022
Peripheral nerve injury is a challenging orthopedic condition that can be treated by autograft transplantation, a gold standard treatment in the current clinical setting.
Zhi Yao, Weihao Yuan, Jiankun Xu, Wenxue Tong, Jie Mi, P. Ho, D. H. Chow, Ye Li, Hao Yao, Xu Li, Shunxiang Xu, Jiaxin Guo, Qingtang Zhu, L. Bian, Ling Qin   +14 more
semanticscholar   +1 more source

Peripheral Nerve Injury Treatments and Advances: One Health Perspective

International Journal of Molecular Sciences, 2021
Peripheral nerve injuries (PNI) can have several etiologies, such as trauma and iatrogenic interventions, that can lead to the loss of structure and/or function impairment.
B. Lopes, P. Sousa, R. Alvites, M. Branquinho, A. Sousa, C. Mendonça, L. Atayde, A. Luís, A. Varejão, A. Maurício   +9 more
semanticscholar   +1 more source

Diagnostic Pathology of Tumors of Peripheral Nerve.

Neurosurgery, 2021
Neoplasms of the peripheral nervous system represent a heterogenous group with a wide spectrum of morphological features and biological potential. They range from benign and curable by complete excision (schwannoma and soft tissue perineurioma) to benign
Sarra Belakhoua, F. Rodriguez
semanticscholar   +1 more source

Management of chronic knee pain caused by postsurgical or posttraumatic neuroma of the infrapatellar branch of the saphenous nerve

Journal of Orthopaedic Surgery and Research, 2021
Purpose Injury to the infrapatellar branch of the saphenous nerve (IBSN) is a relatively common complication after knee surgery, which can interfere with patient satisfaction and functional outcome. In some cases, injury to the IBSN can lead to formation
G. J. Regev, D. Ben Shabat, M. Khashan, D. Ofir, K. Salame, Y. Shapira, R. Kedem, Z. Lidar, S. Rochkind   +8 more
doaj   +1 more source

Insights Into the Role and Potential of Schwann Cells for Peripheral Nerve Repair From Studies of Development and Injury

Frontiers in Molecular Neuroscience, 2021
Peripheral nerve injuries arising from trauma or disease can lead to sensory and motor deficits and neuropathic pain. Despite the purported ability of the peripheral nerve to self-repair, lifelong disability is common. New molecular and cellular insights
Anjali Balakrishnan, Lauren Belfiore, Tak-Ho Chu, Taylor Fleming, R. Midha, J. Biernaskie, C. Schuurmans   +6 more
semanticscholar   +1 more source

Mechanisms of Schwann cell plasticity involved in peripheral nerve repair after injury

Cellular and Molecular Life Sciences, 2020
The great plasticity of Schwann cells (SCs), the myelinating glia of the peripheral nervous system (PNS), is a critical feature in the context of peripheral nerve regeneration following traumatic injuries and peripheral neuropathies. After a nerve damage,
Gianluigi Nocera, C. Jacob
semanticscholar   +1 more source

Mesenchymal Stem Cell Treatment Perspectives in Peripheral Nerve Regeneration: Systematic Review

International Journal of Molecular Sciences, 2021
Traumatic peripheral nerve lesions affect hundreds of thousands of patients every year; their consequences are life-altering and often devastating and cause alterations in movement and sensitivity.
Andrea Lavorato, Stefania Raimondo, M. Boido, L. Muratori, Giorgia Durante, F. Cofano, F. Vincitorio, S. Petrone, P. Titolo, F. Tartara, A. Vercelli, D. Garbossa   +11 more
semanticscholar   +1 more source