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Peripheral nerve damage resulting in pain, loss of sensation, or motor function may necessitate a reconstruction with a bridging material. The RANGER® Registry was designed to evaluate outcomes following nerve repair with processed nerve allograft ...
B. Safa +24 more
semanticscholar +1 more source
Preclinical study of peripheral nerve regeneration using nerve guidance conduits based on polyhydroxyalkanaotes [PDF]
Nerve guidance conduits (NGCs) are used as an alternative to the “gold standard” nerve autografting, preventing the need for surgical intervention required to harvest autologous nerves.
Lizarraga Valderrama, L. +22 more
core +1 more source
Application of stem cells in peripheral nerve regeneration
Traumatic peripheral nerve injury is a worldwide clinical issue with high morbidity. The severity of peripheral nerve injury can be classified as neurapraxia, axonotmesis or neurotmesis, according to Seddon’s classification, or five different degrees ...
Sheng Yi +6 more
semanticscholar +1 more source
ErbB2 signaling in Schwann cells is mostly dispensable for maintenance of myelinated peripheral nerves and proliferation of adult Schwann cells after injury [PDF]
Neuregulin/erbB signaling is critically required for survival and proliferation of Schwann cells as well as for establishing correct myelin thickness of peripheral nerves during development.
Atanasoski, Suzana +14 more
core +1 more source
Natural-Based Biomaterials for Peripheral Nerve Injury Repair
Peripheral nerve injury treatment is a relevant problem because of nerve lesion high incidence and because of unsatisfactory regeneration after severe injuries, thus resulting in a reduced patient’s life quality.
B. Fornasari +3 more
semanticscholar +1 more source
Mice lacking protease nexin-1 show delayed structural and functional recovery after sciatic nerve crush [PDF]
Multiple molecular mechanisms influence nerve regeneration. Because serine proteases were shown to affect peripheral nerve regeneration, we performed nerve crush experiments to study synapse reinnervation in adult mice lacking the serpin protease nexin-1
Atanasoski, Suzana +7 more
core +1 more source
Lumbosacral Plexogram: An Aid to Reconstructive Nerve Possibilities in the Lower Extremity
Summary:. The lumbosacral plexus is the network of nerves responsible for the motor and sensory function of the pelvis and lower limb. Our observation is that the anatomy of this plexus is less familiar to surgeons than that of the brachial plexus ...
Sami Ramadan, FRCS(Plast) +5 more
doaj +1 more source
Synovial sarcoma of the brachial plexus – a rare tumor in a rare area: a case report
Background Synovial cell sarcomas are usually seen in a juxta-articular location. However, they occur rarely in the head and neck region. Case presentation We report a rare case of brachial plexus synovial sarcoma in a 24-year old South Asian man treated
Sreekanth Raveendran +4 more
doaj +1 more source
While CNS microglia have been extensively studied, relatively little is known about macrophages populating the peripheral nervous system. Here we performed ontogenic, transcriptomic and spatial characterization of sciatic nerve macrophages (snMacs ...
E. Ydens +17 more
semanticscholar +1 more source
Schwannomas are the most common tumors of the peripheral nerves, originating from their support cells, the Schwann cells. The location of the tumor in the vagus nerve is rare.
Roberto Sérgio Martins +3 more
doaj +1 more source

