Results 51 to 60 of about 3,422,495 (345)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Lateral elbow ligament reconstruction for posterolateral rotatory instability: 10 years follow-up in 32 patients

JSES International, 2023
Background: Posterolateral rotatory instability (PLRI) is the most frequent form of both acute and chronic elbow instability. It is due to mechanical incompetence of the lateral collateral ligament.
Manon Tranier, MD, Guillaume Bacle, MD, Emilie Marteau, MD, Clara Sos, MD, Jacky Laulan, MD, Steven Roulet, MD   +5 more
doaj   +1 more source

Nerve Ultrasound in Traumatic and Iatrogenic Peripheral Nerve Injury

Diagnostics, 2020
Peripheral nerve injury is a potentially debilitating disorder that occurs in an estimated 2–3% of all patients with major trauma, in a similar percentage of medical procedures.
J. Wijntjes, A. Borchert, N. van Alfen
semanticscholar   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

ErbB2 signaling in Schwann cells is mostly dispensable for maintenance of myelinated peripheral nerves and proliferation of adult Schwann cells after injury [PDF]

, 2006
Neuregulin/erbB signaling is critically required for survival and proliferation of Schwann cells as well as for establishing correct myelin thickness of peripheral nerves during development.
Atanasoski, Suzana, Birchmeier, C., Garratt, Alistair N., Birchmeier, Carmen, Suter, U., Sirkowski, E., Scherer, Steven S., Atanasoski, S., Suter, Ueli, Scherer, S.S., Sirkowski, Erich, Garratt, A.N., S. Atanasoski, Leone, Dino, Leone, D., Atanasoski S, Birchmeier C, Suter U, Scherer SS, Garratt AN, Leone D, Sirkowski E   +21 more
core   +1 more source

Peripheral neuropathies of childhood [PDF]

, 2009
Includes synopsis.Incldues bibliographical references (p. 195-220).Peripheral nerve disease was described by Galen (AD 130-200) over a thousand years ago.(3) Detailed anatomical illustrations were documented by Andreas Vesalius in his major work 'De ...
Wilmshurst, Jo
core   +1 more source

Health-related quality of life in patients with peripheral nerve tumors: results from the German multicentric Peripheral Nerve Tumor Registry

Frontiers in Oncology
ObjectivePeripheral nerve tumors (PNTs) are rare diseases. So far, no multicenter data on diagnostics, the efficacy of treatment, long-term outcomes, and health-related quality of life (HRQoL) exist.
Nadja Grübel, Gregor Antoniadis, Uerschels AK, Benjamin Mayer, Ralph König, Christian Rainer Wirtz, Andrej Pala, Nora F. Dengler, Maria Teresa Pedro   +8 more
doaj   +1 more source

Peripheral nerve repair throughout the body with processed nerve allografts: Results from a large multicenter study

Microsurgery, 2020
Peripheral nerve damage resulting in pain, loss of sensation, or motor function may necessitate a reconstruction with a bridging material. The RANGER® Registry was designed to evaluate outcomes following nerve repair with processed nerve allograft ...
B. Safa, Sonu A Jain, Mihir J. Desai, J. Greenberg, T. Niacaris, Jason A. Nydick, F. Leversedge, David M. Megee, J. Zoldos, B. Rinker, Desirae M. McKee, Brendan J. Mackay, J. Ingari, L. Nesti, M. Cho, Ian L. Valerio, Dennis S. Kao, Y. Elsheikh, Renata V. Weber, J. Shores, J. Styron, W. Thayer, Wojciech H. Przylecki, H. Hoyen, G. Buncke   +24 more
semanticscholar   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Intraoperative 3D Navigation‐Guided Resection of Enlarged Transverse Process for Treating Bertolotti Syndrome Unresponsive to Noninvasive Treatments: Case Report

Clinical Case Reports
Bertolotti syndrome is a lumbosacral anomaly that induces persistent lumbar pain. This case describes 3D navigation‐guided resection of an enlarged transverse process.
Jakub Jankowski, Marcin Glin, Natalia Maślanek, Wiktoria Chyra, Agnieszka Pawełczyk, Maciej Radek   +5 more
doaj   +1 more source