Results 41 to 50 of about 2,424,061 (363)

Characterising cellular and molecular features of human peripheral nerve degeneration

Acta Neuropathologica Communications, 2020
Nerve regeneration is a key biological process in those recovering from neural trauma. From animal models it is known that the regenerative capacity of the peripheral nervous system (PNS) relies heavily on the remarkable ability of Schwann cells to ...
Matthew B. Wilcox, Simão G Laranjeira, Tuula M. Eriksson, Kristjan R. Jessen, Rhona Mirsky, Tom J. Quick, James B. Phillips   +6 more
doaj   +1 more source

Peripheral nerve surgery in Serbia: “Think global, act local” and the privilege of service

Brain and Spine, 2022
Introduction: The phrase “think globally, act locally”, which has often been used to refer to conservation of the environment, highlights the importance of maintaining a holistic perspective and stipulates that each individual has a role to play in their
Lukas Rasulić, Mariano Socolovsky, Christian Heinen, Andreas Demetriades, Milan Lepić, Nathan A. Shlobin, Andrija Savić, Jovan Grujić, Stefan Mandić-Rajčević, Sanja Lepić, Miroslav Samardžic   +10 more
doaj   +1 more source

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási, Bernadett Borbála Huszti, Gábor Barna, Marko Kavcic, Janez Jazbec, Lennart Lenk, Vera Münch, Sophia Polychronopoulou, Ágnes Márk, Maria Thastrup, Lüder H. Meyer, Kjeld Schmiegelow, Cornelia Eckert, Christina Halsey, Dániel J. Erdélyi   +14 more
wiley   +1 more source

Increased Risk of Sarcomas in Children With Congenital Anomalies: Findings From the Genetic Overlap Between Anomalies and Cancer in Kids (GOBACK) Registry Linkage Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure We
Russ Wolters, Ji Yun Tark, Tiffany M. Chambers, Tania A. Desrosiers, Michael E. Scheurer, Charles Shumate, Wendy N. Nembhard, Mahsa M. Yazdy, Eirini Nestoridi, Amanda E. Janitz, Jean Paul Tanner, Russell S. Kirby, Jason L. Salemi, Yao Yu, Chad D. Huff, Sharon E. Plon, Philip J. Lupo, Jeremy M. Schraw   +17 more
wiley   +1 more source

Climbing-inspired twining electrodes using shape memory for peripheral nerve stimulation and recording

Science Advances, 2019
Proposed 3D neural electrode can self-climb onto peripheral nerve driven by body temperature and form flexible neural interface. Peripheral neuromodulation has been widely used throughout clinical practices and basic neuroscience research.
Yingchao Zhang, Ning Zheng, Yu Cao, Fengle Wang, Peng Wang, Yinji Ma, Bingwei Lu, G. Hou, Zizheng Fang, Ziwei Liang, Mengkun Yue, Yan Li, Ying Chen, Ji Fu, Jian Wu, Tao Xie, Xue Feng   +16 more
semanticscholar   +1 more source

Lateral elbow ligament reconstruction for posterolateral rotatory instability: 10 years follow-up in 32 patients

JSES International, 2023
Background: Posterolateral rotatory instability (PLRI) is the most frequent form of both acute and chronic elbow instability. It is due to mechanical incompetence of the lateral collateral ligament.
Manon Tranier, MD, Guillaume Bacle, MD, Emilie Marteau, MD, Clara Sos, MD, Jacky Laulan, MD, Steven Roulet, MD   +5 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Modern Trends for Peripheral Nerve Repair and Regeneration: Beyond the Hollow Nerve Guidance Conduit

Frontiers in Bioengineering and Biotechnology, 2019
Peripheral nerve repair and regeneration remains among the greatest challenges in tissue engineering and regenerative medicine. Even though peripheral nerve injuries (PNIs) are capable of some degree of regeneration, frail recovery is seen even when the ...
Cristiana R. Carvalho, J. Oliveira, R. Reis   +2 more
semanticscholar   +1 more source

Comprehensive neurosurgical and visceral surgical therapy of retroperitoneal nerve tumors: a descriptive and retrospective analysis

World Journal of Surgical Oncology
Nerve tumors in the retroperitoneal space are a rarity. Radical surgery according to soft tissue tumors can lead to persistent pain and neurological deficits.
Martin Petkov, Marko Kornmann, Ute Marlies Bäzner, Lena Minzenmay, Andrej Pala, Maria Teresa Pedro, Christian Rainer Wirtz, Gregor Antoniadis   +7 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source