Results 31 to 40 of about 654,393 (359)

Schwann cell mitochondrial metabolism supports long-term axonal survival and peripheral nerve function [PDF]

, 2011
Mitochondrial dysfunction is a common cause of peripheral neuropathies. While the role of neuron and axonal mitochondria in peripheral nerve disease is well appreciated, whether Schwann cell (SC) mitochondrial deficits contribute to peripheral ...
Baloh, Robert H, Golden, Judith P, Hunter, Daniel A, Milbrandt, Jeffrey, Schmidt, Robert E, Viader, Andreu   +5 more
core   +2 more sources

Tryptophan metabolite atlas uncovers organ, age, and sex‐specific variations

FEBS Open Bio, EarlyView.
Tryptophan metabolites were analyzed across twelve organs, the central nervous system, and serum in male and female mice at three life stages. We found tissue‐, sex‐, and age‐specific differences, including increased indole‐3‐pyruvate and kynurenine in aging males.
Lizbeth Perez‐Castro, Afshan F. Nawas, Jessica A. Kilgore, Pedro A. S. Nogueira, M.Carmen Lafita‐Navarro, Paul H. Acosta, Roy Garcia, Noelle S. Williams, Maralice Conacci‐Sorrell   +8 more
wiley   +1 more source

Development and training of a machine learning algorithm to identify patients at risk for recurrence following an arthroscopic Bankart repair (CLEARER): protocol for a retrospective, multicentre, cohort study

BMJ Open, 2022
Introduction Shoulder instability is a common injury, with a reported incidence of 23.9 per 100 000 person-years. There is still an ongoing debate on the most effective treatment strategy.
, S Nakagawa, L Rossi, Michel P J van den Bekerom, H Nakamura, A Lin, M Gotoh, Y V Kleinlugtenbelt, M Loppini, Job N Doornberg, P MacDonald, Laurent Lafosse, A Stone, Sanne H van Spanning, Lukas P E Verweij, Laurens J H Allaart, Laurent A M Hendrickx, George S Athwal, Thibault Lafosse, Geert Alexander Buijze, T Flinkillä, B R Waterman, B Owens, I Pasqualini, M Scheibel, M Minkus, J S Shaha, M A Ruiz Ibán, R T Li, J M Woodmass, J Phadnis, C Hatrick, T P van Iersel   +32 more
doaj   +1 more source

Aligned cellular and acellular collagen guidance substrates for peripheral nerve repair [PDF]

, 2011
There is a clinical demand to shorten the delay of reinnervation and improve functional recovery after peripheral nerve injury. A peripheral nerve repair device with the ability to direct and promote axon growth across a lesion would be a promising ...
Georgiou, Melanie, Golding, Jon, Loughlin, Jane, Phillips, James   +3 more
core  

Interfacing peripheral nerve with macro-sieve electrodes following spinal cord injury [PDF]

, 2017
Macro-sieve electrodes were implanted in the sciatic nerve of five adult male Lewis rats following spinal cord injury to assess the ability of the macro-sieve electrode to interface regenerated peripheral nerve fibers post-spinal cord injury. Each spinal
Birenbaum, Nathan K, MacEwan, Matthew R, Ray, Wilson Z   +2 more
core   +3 more sources

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Comprehensive neurosurgical and visceral surgical therapy of retroperitoneal nerve tumors: a descriptive and retrospective analysis

World Journal of Surgical Oncology
Nerve tumors in the retroperitoneal space are a rarity. Radical surgery according to soft tissue tumors can lead to persistent pain and neurological deficits.
Martin Petkov, Marko Kornmann, Ute Marlies Bäzner, Lena Minzenmay, Andrej Pala, Maria Teresa Pedro, Christian Rainer Wirtz, Gregor Antoniadis   +7 more
doaj   +1 more source

Nerve localization techniques for peripheral nerve block and possible future directions [PDF]

, 2015
Ultrasound guidance is now a standard nerve localization technique for peripheral nerve block (PNB). Ultrasonography allows simultaneous visualization of the target nerve, needle, local anesthetic injectate and surrounding anatomical structures. Accurate
Helen, Lisa, Moore, Eric J., O'Donnell, Brian D.   +2 more
core   +1 more source

Research progress on the metabolic transformation of Shenling Baizhu San under the influence of the gut microbiota

Advanced Chinese Medicine, EarlyView.
Abstract The gut microbiota plays a pivotal role in maintaining host metabolic homeostasis and overall physiological functions. Shenling Baizhu San (SLBZS), a time‐honored classical prescription for tonifying Qi, strengthening the spleen, removing dampness, and arresting diarrhea, has shown broad clinical efficacy in digestive disorders.
Jinlan Di, Xiaochun Zhang
wiley   +1 more source

Health-related quality of life in patients with peripheral nerve tumors: results from the German multicentric Peripheral Nerve Tumor Registry

Frontiers in Oncology
ObjectivePeripheral nerve tumors (PNTs) are rare diseases. So far, no multicenter data on diagnostics, the efficacy of treatment, long-term outcomes, and health-related quality of life (HRQoL) exist.
Nadja Grübel, Gregor Antoniadis, Uerschels AK, Benjamin Mayer, Ralph König, Christian Rainer Wirtz, Andrej Pala, Nora F. Dengler, Maria Teresa Pedro   +8 more
doaj   +1 more source