Results 251 to 260 of about 337,673 (396)

Midkine‐Mediated Microglia Activation after Renal Injury Promotes Cognitive Impairment Following Ischemic Renal Injury

Advanced Science, EarlyView.
The mechanism of secondary cognitive impairment following AKI. When renal ischemic injury progresses to fibrosis, renal fibroblasts and damaged tubular cells secrete MDK, which circulates through the bloodstream, crosses the damaged BBB, and accumulates in the hippocampus tissue (an area crucial for learning and memory).
Li Lu, Bixiao Liu, Yu Yang, Tao Meng, Yuanyuan Chang, Yao Peng, Jia Guo, Zhuqing Wang, Hongqian Guo, Liuhua Zhou, Xiaozhi Zhao   +10 more
wiley   +1 more source

Assessment, management, and rehabilitation of traumatic peripheral nerve injuries for non-surgeons. [PDF]

Muscle Nerve
Bateman EA, Pripotnev S, Larocerie-Salgado J, Ross DC, Miller TA.   +4 more
europepmc   +1 more source

Morphine Tolerance Gated through EZH2‐Mediated Suppression of Trpc5 in Spinal GABAergic Interneurons in Male Mice

Advanced Science, EarlyView.
Chronic morphine suppresses Trpc5 in spinal GABAergic interneurons via EZH2‐mediated histone modification, reducing Ca2+ influx and GABA release. TRPC5 activation enhances morphine analgesia, while EZH2 inhibition restores efficacy and reverses tolerance.
Li Wan, Mengyao Zhang, Haiyue Guo, Yan Xu, Chenjie Xu, Fan Hu, Yinbing Pan, Xian Wang, Wentao Liu, Chun‐Yi Jiang   +9 more
wiley   +1 more source

Engineering 3D-printed standalone conductive nerve guides using soft bioinks for peripheral nerve injuries.

Mater Adv
Li L, Hernandez A, Grevsmuehl R, Kou YT, Song S.   +4 more
europepmc   +1 more source

Evaluation of traumatic peripheral nerve injuries in terms of Forensic Medicine. [PDF]

Ulus Travma Acil Cerrahi Derg
Bulutluöz EG, Balandız H, Özsoy S.
europepmc   +1 more source

Neurobiology of peripheral nerve injury, regeneration, and functional recovery: from bench top research to bedside application.

, 2013
Wale A R Sulaiman, Tessa Gordon
openalex   +1 more source

Green Tea Polyphenols Promote Functional Recovery from Peripheral Nerve Injury in Rats

, 2020
Jinhong Chen, Rongyuan Yang, Honghan Li, Jie Lao   +3 more
openalex   +2 more sources

Management of peripheral nerve injury

Journal of Clinical Orthopaedics and Trauma, 2019
openaire   +3 more sources

Constructing Dual‐Atomic Fe─Fe Sites Nanozyme for Targeted Osteoarthritis Therapy through Mitigating Oxidative Stress and Cartilage Degeneration

Advanced Science, EarlyView.
A novel bimetallic nanozyme (Fe2–NCs) with well‐defined Fe–Fe active sites is synthesized through a host–guest coordination strategy, which exhibits an exceptional therapeutic efficacy in osteoarthritis therapy. Experimental and theoretical analyses uncover the intrinsic catalytic mechanism at the atomic level, offering fundamental insights and design ...
Ting Ying, Qi Wang, Dejian Li, Yao Wang, Pengfang Zhang, Chengqing Yi, Rui Zhu   +6 more
wiley   +1 more source

Exploration of Novel Biomarkers Through a Precision Medicine Approach Using Multi‐Omics and Brain Organoids in Patients With Atypical Depression and Psychotic Symptoms

Advanced Science, EarlyView.
This study examines major depressive disorder with atypical features and psychotic symptoms through a multi‐omics precision medicine approach. By integrating clinical assessments, WBC scRNA‐seq, plasma proteomics, and brain organoid models, it uncovers immune dysregulation, synaptic protein alterations, and stress‐sensitive neuronal changes.
Insook Ahn, Soyeon Chang, Jiyoung Lee, Seok‐Ho Choi, Jinju Han, Yangsik Kim   +5 more
wiley   +1 more source