Spatiotemporal Adaptations‐Driven Dynamic Thra Activation Simulates a Skin Wound Healing Response
This study uncovers the thyroid hormone receptor Thra as a pivotal regulator that spatiotemporally orchestrates dual‐phase skin repair. Epidermal Thra accelerates barrier restoration via glutathione‐driven keratin assembly, while dermal Thra establishes angiogenic niches through SAA3‐FN1‐mediated matrix remodeling.
Zeming Li+15 more
wiley +1 more source
GFRα1 Promotes Axon Regeneration after Peripheral Nerve Injury by Functioning as a Ligand. [PDF]
Suzuki T+5 more
europepmc +1 more source
Astrocytic ET‐1 System Determines Microglia Phenotype Following Spinal Cord Injury
The study reveals that astrocytic ET‐1 system is solely activated by thrombin following SCI via RhoA/NF‐κB and MAPKs/NF‐κB signal pathway. The release of astrocytic ET‐1 drives microglia polarization toward M1 phenotype through YAP signaling via ETA and ETB receptors.
Bingqiang He+11 more
wiley +1 more source
Selective RNAi silencing of Schwann cell Piezo1 alleviates mechanical hypersensitization following peripheral nerve injury. [PDF]
Itson-Zoske B+8 more
europepmc +1 more source
Vertical Electrolyte‐Gated Transistors: Structures, Materials, Integrations, and Applications
Vertically structured electrolyte‐gated transistors exhibit significantly improved electrical performance compared to their planar counterparts by decoupling the channel length from the resolutions of the fabrication techniques. Herein, recent progress on the vertical electrolyte‐gated transistors is reviewed from the aspects of device structures ...
Bin Bao+7 more
wiley +1 more source
Role of Intraoperative Nerve Monitoring in Preventing Peripheral Nerve Injury During Total Hip Arthroplasty in High-Risk Patients. [PDF]
Harada T+7 more
europepmc +1 more source
Geriatric surgical risk factors and outcomes were compared between the US and Japanese databases. Geriatric‐associated preoperative variables and outcomes similarly increased with age. Mobility and functional domains differed between the two databases. ABSTRACT Backgrounds Incidence of malignant disease in older patients has been increasing.
Yasuhide Kofunato+13 more
wiley +1 more source
Skeletal muscle reprogramming enhances reinnervation after peripheral nerve injury. [PDF]
Mehrotra P+14 more
europepmc +1 more source
Fluorescence Guided Surgery in Gastric Cancer: What Do We Have and What Can We Do?
ABSTRACT Background and Objective Fluorescence imaging has emerged as a valuable adjunct in gastric surgery, enhancing resection precision and oncologic outcomes. However, the use of indocyanine green (ICG) remains controversial due to uncertainties in efficacy and administration. A lack of standardized protocols persists.
Chun Zhuang, Han‐Kwang Yang
wiley +1 more source
High-grade B-cell lymphoma manifested as peripheral nerve injury: A case report. [PDF]
Luo H, Li S, Liu B.
europepmc +1 more source