Results 71 to 80 of about 286,538 (260)

Conditional gene deletion reveals functional redundancy of GABAB receptors in peripheral nociceptors in vivo [PDF]

open access: yes, 2009
Background Gamma-aminobutyric acid (GABA) is an important inhibitory neurotransmitter which mainly mediates its effects on neurons via ionotropic (GABAA) and metabotropic (GABAB) receptors.
Bernhard Bettler   +9 more
core   +3 more sources

Porcine decellularized nerve matrix hydrogel attenuates neuroinflammation after peripheral nerve injury by inhibiting the TLR4/MyD88/NF-κB axis

open access: yesNeural Regeneration Research
Peripheral nerve injury causes severe neuroinflammation and has become a global medical challenge. Previous research has demonstrated that porcine decellularized nerve matrix hydrogel exhibits excellent biological properties and tissue specificity ...
Rui Li   +9 more
doaj   +1 more source

Systemic functional enrichment and ceRNA network identification following peripheral nerve injury

open access: yesMolecular Brain, 2018
Peripheral nerve injury is a worldwide clinical issue that impacts patients’ quality of life and causes huge society and economic burden. Injured peripheral nerves are able to regenerate by themselves.
Tianmei Qian   +3 more
doaj   +1 more source

Guillain-Barré syndrome: a century of progress [PDF]

open access: yes, 2016
In 1916, Guillain, Barré and Strohl reported on two cases of acute flaccid paralysis with high cerebrospinal fluid protein levels and normal cell counts — novel findings that identified the disease we now know as Guillain–Barré syndrome (GBS).
A Campbell   +91 more
core   +1 more source

Peripheral nerve injuries in haemophilia.

open access: yesBlood transfusion = Trasfusione del sangue, 2014
The most common form of nerve damage in haemophilia is peripheral neuropathy (peripheral nerve injury), which mainly affects the upper and lower limbs. The purpose of this review is to provide information on the aspects of haemophilia management which may have an influence on or relationship with peripheral nerve injuries (replacement therapy ...
openaire   +2 more sources

Biodegradable Conduit Small Gap Tubulization for Peripheral Nerve Mutilation: A Substitute for Traditional Epineurial Neurorrhaphy

open access: yesInternational Journal of Medical Sciences, 2013
Nerve regeneration and re-innervation are usually difficult after peripheral nerve injury. Epineurium neurorrhaphy to recover the nerve continuity is the traditional choice of peripheral nerve mutilation without nerve defects, whereas the functional ...
Peixun Zhang, Na Han, Tianbing Wang, Feng Xue, Yuhui Kou, Yanhua Wang, Xiaofeng Yin, Laijin Lu, Guanglei Tian, Xu Gong, Shanlin Chen, Yu Dang, Jianping Peng, Baoguo Jiang
doaj  

Artificial intelligence-assisted repair of peripheral nerve injury: a new research hotspot and associated challenges

open access: yesNeural Regeneration Research
Artificial intelligence can be indirectly applied to the repair of peripheral nerve injury. Specifically, it can be used to analyze and process data regarding peripheral nerve injury and repair, while study findings on peripheral nerve injury and repair ...
Yang Guo   +5 more
doaj   +1 more source

Therapeutic strategies for peripheral nerve injury: decellularized nerve conduits and Schwann cell transplantation

open access: yesNeural Regeneration Research, 2019
In recent years, the use of Schwann cell transplantation to repair peripheral nerve injury has attracted much attention. Animal-based studies show that the transplantation of Schwann cells in combination with nerve scaffolds promotes the repair of ...
Gong-Hai Han   +6 more
doaj   +1 more source

BDNF-loaded chitosan-based mimetic mussel polymer conduits for repair of peripheral nerve injury

open access: yesFrontiers in Cell and Developmental Biology
Care for patients with peripheral nerve injury is multifaceted, as traditional methods are not devoid of limitations. Although the utilization of neural conduits shows promise as a therapeutic modality for peripheral nerve injury, its efficacy as a ...
Lei Li   +7 more
doaj   +1 more source

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