Dynein promotes sustained axonal growth and Schwann cell remodeling early during peripheral nerve regeneration. [PDF]
Following injury, axons of the peripheral nervous system have retained the capacity for regeneration. While it is well established that injury signals require molecular motors for their transport from the injury site to the nucleus, whether kinesin and ...
Melissa Ducommun Priest+3 more
doaj +1 more source
Spotlight on nerves: Portable multispectral optoacoustic imaging of peripheral nerve vascularization and morphology [PDF]
Various morphological and functional parameters of peripheral nerves and their vascular supply are indicative of pathological changes due to injury or disease. Based on recent improvements in optoacoustic image quality, we explore the ability of multispectral optoacoustic tomography, in tandem with ultrasound imaging (OPUS), to investigate the vascular
arxiv
A model of electrical impedance tomography on peripheral nerves for a neural-prosthetic control interface [PDF]
Objective: A model is presented to evaluate the viability of using electrical impedance tomography (EIT) with a nerve cuff to record neural activity in peripheral nerves. Approach: Established modelling approaches in neural-EIT are expanded on to be used, for the first time, on myelinated fibres which are abundant in mammalian peripheral nerves and ...
arxiv +1 more source
Autophagy-targeting modulation to promote peripheral nerve regeneration
Nerve regeneration following traumatic peripheral nerve injuries and neuropathies is a complex process modulated by diverse factors and intricate molecular mechanisms.
Yan Chen, Hongxia Deng, Nannan Zhang
doaj +1 more source
A novel statistical methodology for quantifying the spatial arrangements of axons in peripheral nerves [PDF]
A thorough understanding of the neuroanatomy of peripheral nerves is required for a better insight into their function and the development of neuromodulation tools and strategies. In biophysical modeling, it is commonly assumed that the complex spatial arrangement of myelinated and unmyelinated axons in peripheral nerves is random, however, in reality ...
arxiv
Optical coherence tomography imaging of evoked neural activity in sciatic nerve of rat [PDF]
Significance: Imaging neural activity in myelinated tissue using optical coherence tomography (OCT) creates new possibilities for functional imaging in the peripheral and central nervous systems. Aim: To investigate changes in OCT images in response to evoked neural activity in sciatic nerve of rat in vitro.
arxiv +1 more source
Introduction We investigated the possible beneficial effect of dimethylsulfoxide (DMSO) on peripheral nerve repair in rats. Methods: Seventy rats were divided into four groups: control, sham, DMSO-L, and DMSO-IP. Except in the control group, nerve repair
Elif Sanli+2 more
doaj +1 more source
The role of kinases in peripheral nerve regeneration: mechanisms and implications
Peripheral nerve injury disease is a prevalent traumatic condition in current medical practice. Despite the present treatment approaches, encompassing surgical sutures, autologous nerve or allograft nerve transplantation, tissue engineering techniques ...
Xu Zhang+3 more
doaj +1 more source
Automatic Ultrasound Image Segmentation of Supraclavicular Nerve Using Dilated U-Net Deep Learning Architecture [PDF]
Automated object recognition in medical images can facilitate medical diagnosis and treatment. In this paper, we automatically segmented supraclavicular nerves in ultrasound images to assist in injecting peripheral nerve blocks. Nerve blocks are generally used for pain treatment after surgery, where ultrasound guidance is used to inject local ...
arxiv
Fibro-adipogenic progenitors (FAPs) are muscle-resident mesenchymal progenitors that can contribute to muscle tissue homeostasis and regeneration, as well as postnatal maturation and lifelong maintenance of the neuromuscular system.
Kyusang Yoo+11 more
doaj +1 more source