Results 81 to 90 of about 148,079 (169)

Transcriptomic Landscapes of Immune Response and Axonal Regeneration by Integrative Analysis of Molecular Pathways and Interactive Networks Post-sciatic Nerve Transection

open access: yesFrontiers in Neuroscience, 2018
Potential interaction between immune response and axonal regeneration has recently attracted much attention in peripheral nervous system (PNS). Previously, global mRNA expression changes in proximal nerve segments were profiled and merely focused on the ...
Qi Guo   +13 more
doaj   +1 more source

Hepatocyte Growth Factor (HGF) Promotes Peripheral Nerve Regeneration by Activating Repair Schwann Cells

open access: yesScientific Reports, 2018
During the peripheral nerve regeneration process, a variety of neurotrophic factors play roles in nerve repair by acting on neuronal or non-neuronal cells.
K. Ko   +4 more
semanticscholar   +1 more source

The role of exercise on peripheral nerve regeneration: from animal model to clinical application

open access: yesHeliyon, 2021
Peripheral nerve injury is a complex condition with a variety of signs and symptoms depending on the severity and nerves involved. Peripheral nerve damage may lead to sensory and motor functions deficits and even lifelong disability, causing important ...
Grazia Maugeri   +7 more
doaj  

Metabolomic signature of type 1 diabetes-induced sensory loss and nerve damage in diabetic neuropathy [PDF]

open access: yesarXiv, 2018
Diabetic-induced peripheral neuropathy (DPN) is a diabetic late complication. The molecular mechanisms underlying the pathophysiology of nerve damage & sensory loss remain largely unclear. Recently, alterations in metabolic flux have gained attention a basis for organ damage in diabetes; however, peripheral sensory neurons have not been adequately ...
arxiv  

Biomimetic Photocurable Three-Dimensional Printed Nerve Guidance Channels with Aligned Cryomatrix Lumen for Peripheral Nerve Regeneration.

open access: yesACS Applied Materials and Interfaces, 2018
Repair and regeneration of critically injured peripheral nerves is one of the most challenging reconstructive surgeries. Currently available and FDA approved nerve guidance channels (NGCs) are suitable for small gap injuries, and their biological ...
Anamika Singh   +8 more
semanticscholar   +1 more source

Stem Cell Transplantation for Peripheral Nerve Regeneration: Current Options and Opportunities

open access: yesInternational Journal of Molecular Sciences, 2017
Peripheral nerve regeneration is a complicated process highlighted by Wallerian degeneration, axonal sprouting, and remyelination. Schwann cells play an integral role in multiple facets of nerve regeneration but obtaining Schwann cells for cell-based ...
Liangfu Jiang, Salazar Jones, X. Jia
semanticscholar   +1 more source

Application of Mesenchymal Stem Cell-Derived Schwann Cell-like Cells Spared Neuromuscular Junctions and Enhanced Functional Recovery After Peripheral Nerve Injury

open access: yesCells
In general, the nerve cells of the peripheral nervous system regenerate normally within a certain period after the physical damage of their axon.
Yu Hwa Nam   +8 more
doaj   +1 more source

Local administration of icariin contributes to peripheral nerve regeneration and functional recovery

open access: yesNeural Regeneration Research, 2015
Our previous study showed that systemic administration of the traditional Chinese medicine Epimedium extract promotes peripheral nerve regeneration. Here, we sought to explore the therapeutic effects of local administration of icariin, a major component ...
Bo Chen   +9 more
doaj   +1 more source

Hypoxia-inducible factor 1a protects peripheral sensory neurons from diabetic peripheral neuropathy by suppressing accumulation of reactive oxygen species [PDF]

open access: yesarXiv, 2018
Diabetic peripheral neuropathy (DPN) is one of the most common diabetic complications. Mechanisms underlying nerve damage and sensory loss following metabolic dysfunction remain large unclear. Recently, hyperglycemia-induced mitochondrial dysfunction and the generation of ROS have gained attention as possible mechanisms of organ damage in diabetes ...
arxiv  

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