Results 221 to 230 of about 511,513 (357)

Brain-derived extracellular vesicles potentially mediate crosstalk with peripheral organs in neurodegenerative diseases. [PDF]

Front Cell Dev Biol
Hamdalla RH, Bhaskar VB, Tian C.
europepmc   +1 more source

Damage of cutaneous peripheral nervous system evolves differently according to the disease phase and subset of systemic sclerosis [PDF]

, 2005
L. Ibba Manneschi, Angela Del Rosso, Anna Franca Milia, Akio Tani, D. Nosi, Alberto Moggi Pignone, Sergio Generini, Roberto Giacomelli, M. Matucci Cerinic   +8 more
openalex   +1 more source

NAD⁺ Reduction in Glutamatergic Neurons Induces Lipid Catabolism and Neuroinflammation in the Brain via SARM1

Advanced Science, EarlyView.
NAD⁺ homeostasis maintains neuronal integrity through opposing actions of NMNAT2 and SARM1. Loss of NMNAT2 in glutamatergic neurons reprograms cortical metabolism from glucose to lipid catabolism, depletes lipid stores, and triggers inflammation and neurodegeneration.
Zhen‐Xian Niou, Sen Yang, Andrea Enriquez, Nino A. Espinas, Anoosha Sri, Caliel D. Hines, Jason M. Tennessen, Chia‐Shan Wu, Jui‐Yen Huang, Hui‐Chen Lu   +9 more
wiley   +1 more source

Letter to the Editor Regarding: Cognitive Function and Proteomic Changes in Patients with Autoantibody-Positive Neurodegenerative Dementia. [PDF]

Neurol Ther
Lu X, Shen X.
europepmc   +1 more source

Present-day professional lead polyneuropathy — chronic demyelinating disease of peripheral nervous system

, 1997
R. G. Obraztsova, J. I. Borzunova
openalex   +2 more sources

Human Atlas of Tooth Decay Progression: Identification of Cellular Mechanisms Driving the Switch from Dental Pulp Repair Toward Irreversible Pulpitis

Advanced Science, EarlyView.
Tooth decay progression transforms the dental pulp response from repair to fibrosis. At early stages, stromal cells reprogram to repair the extra cellular matrix (ECM), blood vessels, and nerves, remodel and grow, keeping repair possible. In advanced decay, hypoxia, and vessel regression, in complement with an immune switch, fuel nerve degeneration and
Hoang Thai Ha, Sofya Kosmynina, Amandine Verocq, Keremsah Ozen, Ines Tekia, Hugo Bussy, Marie Ramirez, Dima Sabbah, Chloe Goemans, Valerie Vandenbempt, Esteban N. Gurzov, Sumeet Pal Singh, Nicolas Baeyens   +12 more
wiley   +1 more source

Identification of Comprehensive Landscape of Peripheral Immunity and Chemokine-Related Genes in Amyotrophic Lateral Sclerosis. [PDF]

Immunotargets Ther
Yang X, Huang S, Wang Y, Yuan J, Yao X.
europepmc   +1 more source

Washington University Medical Alumni Quarterly, July 1951 [PDF]

, 1951

core   +1 more source

Heat Stress Modulates WDR5‐Mediated H3K4me3 Modification to Induce Melanogenesis via Activating CX3CL1/CX3CR1 Axis

Advanced Science, EarlyView.
This study elucidates the mechanism by which heat stress regulates skin pigmentation: heat stress upregulates CX3CL1 through the MYC‐WDR5‐H3K4me3 axis, thereby activating the CX3CL1/CX3CR1‐JNK signaling pathway and ultimately promoting melanogenesis. These findings provide novel potential therapeutic targets for pigmentary skin disorders.
Yushan Zhang, Ling Jiang, Yibo Hu, Chuhan Fu, Jinhua Huang, Jing Chen, Qinghai Zeng   +6 more
wiley   +1 more source

Beyond barriers: when neurons act immune and immunity acts neural. [PDF]

Signal Transduct Target Ther
Kim SW, Seok SH.
europepmc   +1 more source