Cholinergic Modulation of the Immune System in Neuroinflammatory Diseases
Frequent diseases of the CNS, such as Alzheimer’s disease, Parkinson’s disease, multiple sclerosis, and psychiatric disorders (e.g., schizophrenia), elicit a neuroinflammatory response that contributes to the neurodegenerative disease process itself. The
Marcella Reale, Erica Costantini
doaj +1 more source
Protective potential of glucagon like peptide 2 (GLP-2) against the neurodegeneration [PDF]
Neurodegeneration consists in loss of neuron specific types, pattern and distribution, leading to progressive dysfunctions of the central nervous system.
Amato, Antonella, Mulè, Flavia
core +1 more source
Impairment of the Peripheral Nervous System in Creutzfeldt-Jakob Disease [PDF]
The clinical manifestations of Creutzfeldt-Jakob disease (CJD) primarily reflect involvement of the central nervous system. The coexistence of CJD with peripheral nervous system involvement has also been reported.To analyze peripheral neuron electrophysiologic changes and to compare these data with neuropathologic features of spinal motor neurons in ...
M. Niewiadomska+10 more
openaire +3 more sources
Autoimmune Disorders of the Nervous System: Pathophysiology, Clinical Features, and Therapy
Remarkable discoveries over the last two decades have elucidated the autoimmune basis of several, previously poorly understood, neurological disorders.
Satyakam Bhagavati
doaj +1 more source
Novel Advancements in Three-Dimensional Neural Tissue Engineering and Regenerative Medicine [PDF]
Neurological diseases and injuries present some of the greatest challenges in modern medicine, often causing irreversible and lifelong burdens in the people whom they afflict. These diagnoses have devastating consequences on millions of people each year, and yet there are currently no therapies or interventions that can repair the structure of neural ...
arxiv +1 more source
CAV-2 Vector Development and Gene Transfer in the Central and Peripheral Nervous Systems [PDF]
The options available for genetic modification of cells of the central nervous system (CNS) have greatly increased in the last decade. The current panoply of viral and nonviral vectors provides multifunctional platforms to deliver expression cassettes to
Amani Wehbi+7 more
core +2 more sources
Serum amyloid A primes microglia for ATP-dependent interleukin-1\u3b2 release [PDF]
Acute-phase response is a systemic reaction to environmental/inflammatory insults and involves production of acute-phase proteins, including serum amyloid A (SAA).
A Basu+82 more
core +2 more sources
Peripheral nervous system diseases and pregnancy
113 pregnant women with periferal nervous system diseases(PNSD) are examined. 84 of them had radiculoneuropathy: 48 - lumbosacral segment (LSS), 36 - cervicothoracal segment (CTS), 29 had single and multiple neuropathy (SMN). Almost half cases (49,6%) the symptoms of PNSD first appeared in 2nd trimester.
V. D. Ryzkov+2 more
openaire +3 more sources
Immune checkpoint inhibitors (ICIs) can cause adverse reactions in the nervous system. The incidence rate is 0.1%–12% and 80% of nervous system adverse reactions occur within the first four months of application.
Jiayu Shi+9 more
doaj +1 more source
Neuroinvasion in Prion Diseases: The Roles of Ascending Neural Infection and Blood Dissemination [PDF]
Prion disorders are infectious, neurodegenerative diseases that affect humans and animals. Susceptibility to some prion diseases such as kuru or the new variant of Creutzfeldt-Jakob disease in humans and scrapie in sheep and goats is influenced by ...
González, Lorenzo+2 more
core +4 more sources