Recent Advances in the Diagnosis and Pathogenesis of Neurofibromatosis Type 1 (NF1)-associated Peripheral Nervous System Neoplasms [PDF]
The diagnosis of a neurofibroma or a malignant peripheral nerve sheath tumor (MPNST) often raises the question of whether the patient has the genetic disorder neurofibromatosis type 1 (NF1) as well as how this will impact the patient’s outcome, what their risk is for developing additional neoplasms and whether treatment options differ for NF1 ...
Jody Fromm Longo +3 more
europepmc +6 more sources
Immunolocalization of Laminin in Neoplasms of the Central and Peripheral Nervous Systems [PDF]
Laminin is a basement membrane glycoprotein that is expressed in vitro by immature and neoplastic astrocytes. The expression of laminin in vivo was examined immunohistochemically in normal adult brain and 90 neoplasms of the central and peripheral nervous systems.
Rodney D. McComb, Darell D. Bigner
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Genetically engineered mouse models shed new light on the pathogenesis of neurofibromatosis type I-related neoplasms of the peripheral nervous system [PDF]
Neurofibromatosis type 1 (NF1), the most common genetic disorder affecting the human nervous system, is characterized by the development of multiple benign Schwann cell tumors in skin and large peripheral nerves. These neoplasms, which are termed dermal and plexiform neurofibromas respectively, have distinct clinical courses; of particular note ...
Nicole M Brossier, Steven L. Carroll
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Experiences of navigating anticipations and anxiety among patients having surgery for peripheral nerve tumours [PDF]
Peripheral nerve tumours, most commonly schwannomas and neurofibromas, might present significant challenges by eliciting physical symptoms and emotional distress.
Emanuel Istefan +4 more
doaj +2 more sources
Neurological manifestations in HIV-infected patients: a retrospective cohort study in Northeastern Iran [PDF]
Background Neurological complications are a severe aspect of HIV infection, impacting patient outcomes significantly. This study investigates the prevalence and types of neurological syndromes among HIV-infected patients and their outcomes in ...
Zahra Sadat Mireskandari +4 more
doaj +2 more sources
Tiny needles, major benefits: acupuncture in child health [PDF]
Objective To retrospectively investigate the utilization patterns and clinical indications of acupuncture within the pediatric population in general hospitals from 2015 to 2020, including disease spectrum characteristics and relevance to pediatric ...
Xiaobin Ge +3 more
doaj +2 more sources
Large schwannoma of the median nerve at the distal forearm [PDF]
Introduction. Schwannoma, also known as neurilemmoma, is a rare but one of the most common tumors of the peripheral nerves. It originates from Schwann cells of the peripheral nerve sheaths. Schwannoma mostly occurs in adults between 20 to 70 years of age.
Vulović Dejan +8 more
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Immunohistochemical Study of Ki-67 Labelling Index in Neoplasms of Central Nervous System [PDF]
Introduction: The central nervous system tumours show a varied histopathological spectrum. The cell proliferation index may provide an objective method for assessing tumour biology. The Ki-67 is considered to be the most reliable proliferative marker
Anuradha G Patil +3 more
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