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Recent Advances in the Diagnosis and Pathogenesis of Neurofibromatosis Type 1 (NF1)-associated Peripheral Nervous System Neoplasms. [PDF]
Adv Anat Pathol, 2018 The diagnosis of a neurofibroma or a malignant peripheral nerve sheath tumor (MPNST) often raises the question of whether the patient has the genetic disorder neurofibromatosis type 1 (NF1) as well as how this will impact the patient’s outcome, what their risk is for developing additional neoplasms and whether treatment options differ for NF1 ...
Longo JF +3 more
europepmc +6 more sources
Immunolocalization of Laminin in Neoplasms of the Central and Peripheral Nervous Systems [PDF]
Journal of Neuropathology and Experimental Neurology, 1985 Laminin is a basement membrane glycoprotein that is expressed in vitro by immature and neoplastic astrocytes. The expression of laminin in vivo was examined immunohistochemically in normal adult brain and 90 neoplasms of the central and peripheral nervous systems.
Rodney D. McComb, Darell D. Bigner
openaire +3 more sources
Genetically engineered mouse models shed new light on the pathogenesis of neurofibromatosis type I-related neoplasms of the peripheral nervous system [PDF]
Brain Research Bulletin, 2012 Neurofibromatosis type 1 (NF1), the most common genetic disorder affecting the human nervous system, is characterized by the development of multiple benign Schwann cell tumors in skin and large peripheral nerves. These neoplasms, which are termed dermal and plexiform neurofibromas respectively, have distinct clinical courses; of particular note ...
Nicole M. Brossier, Steven L. Carroll
openaire +4 more sources
Signal mining and analysis of adverse events of Brentuximab Vedotin base on FAERS and JADER databases. [PDF]
PLoS ONEObjectivesBrentuximab Vedotin (BV) is a novel antibody-drug conjugate (ADC) approved for the treatment of classical Hodgkin's lymphoma and systemic anaplastic large cell lymphoma.
Feilong Tan +3 more
doaj +2 more sources
Tiny needles, major benefits: acupuncture in child health [PDF]
BMC PediatricsObjective To retrospectively investigate the utilization patterns and clinical indications of acupuncture within the pediatric population in general hospitals from 2015 to 2020, including disease spectrum characteristics and relevance to pediatric ...
Xiaobin Ge +3 more
doaj +2 more sources
Large schwannoma of the median nerve at the distal forearm [PDF]
Vojnosanitetski Pregled, 2023 Introduction. Schwannoma, also known as neurilemmoma, is a rare but one of the most common tumors of the peripheral nerves. It originates from Schwann cells of the peripheral nerve sheaths. Schwannoma mostly occurs in adults between 20 to 70 years of age.
Vulović Dejan +8 more
doaj +1 more source
Immunohistochemical Study of Ki-67 Labelling Index in Neoplasms of Central Nervous System [PDF]
National Journal of Laboratory Medicine, 2022 Introduction: The central nervous system tumours show a varied histopathological spectrum. The cell proliferation index may provide an objective method for assessing tumour biology. The Ki-67 is considered to be the most reliable proliferative marker
Anuradha G Patil +3 more
doaj +1 more source
BMC Musculoskeletal Disorders, 2023 Background Benign peripheral nerve tumours consist of different types, most commonly Schwannomas. Preoperative Magnetic Resonance Imaging (MRI) is commonly performed before surgery and Pathoanatomical Diagnosis (PAD) confirms the diagnosis. Our aims were
Emanuel Istefan +3 more
doaj +1 more source