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Recent Advances in the Diagnosis and Pathogenesis of Neurofibromatosis Type 1 (NF1)-associated Peripheral Nervous System Neoplasms [PDF]
Advances in Anatomic Pathology, 2018 The diagnosis of a neurofibroma or a malignant peripheral nerve sheath tumor (MPNST) often raises the question of whether the patient has the genetic disorder neurofibromatosis type 1 (NF1) as well as how this will impact the patient’s outcome, what their risk is for developing additional neoplasms and whether treatment options differ for NF1 ...
Jody F, Longo +3 more
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Genetically engineered mouse models shed new light on the pathogenesis of neurofibromatosis type I-related neoplasms of the peripheral nervous system [PDF]
Brain Research Bulletin, 2012 Neurofibromatosis type 1 (NF1), the most common genetic disorder affecting the human nervous system, is characterized by the development of multiple benign Schwann cell tumors in skin and large peripheral nerves. These neoplasms, which are termed dermal and plexiform neurofibromas respectively, have distinct clinical courses; of particular note ...
Nicole M, Brossier, Steven L, Carroll
semanticscholar +5 more sources
Immunolocalization of Laminin in Neoplasms of the Central and Peripheral Nervous Systems [PDF]
Journal of Neuropathology and Experimental Neurology, 1985 Laminin is a basement membrane glycoprotein that is expressed in vitro by immature and neoplastic astrocytes. The expression of laminin in vivo was examined immunohistochemically in normal adult brain and 90 neoplasms of the central and peripheral nervous systems.
R D, McComb, D D, Bigner
semanticscholar +4 more sources
The American journal of pathology, 2016 Comprehensive genomic analyses of common nervous system cancers provide new insights into their pathogenesis, diagnosis, and treatment. Although analogous studies of rare nervous system tumors are needed, there are major barriers to performing such studies.
S. Carroll
openaire +3 more sources
Malignant Peripheral Nervous System Neoplasm [PDF]
, 2020 National Cancer Institute
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Large schwannoma of the median nerve at the distal forearm [PDF]
Vojnosanitetski Pregled, 2023 Introduction. Schwannoma, also known as neurilemmoma, is a rare but one of the most common tumors of the peripheral nerves. It originates from Schwann cells of the peripheral nerve sheaths. Schwannoma mostly occurs in adults between 20 to 70 years of age.
Vulović Dejan +8 more
doaj +1 more source
Pediatric Neurosurgery, 2023 Background: Neurofibromatosis type 1 and neurofibromatosis type 2 are unrelated, distinct genetic disorders characterized by the development of central and peripheral nervous system tumors.
Chelsea Kotch +3 more
semanticscholar +1 more source
Immunohistochemical Study of Ki-67 Labelling Index in Neoplasms of Central Nervous System [PDF]
National Journal of Laboratory Medicine, 2022 Introduction: The central nervous system tumours show a varied histopathological spectrum. The cell proliferation index may provide an objective method for assessing tumour biology. The Ki-67 is considered to be the most reliable proliferative marker
Anuradha G Patil +3 more
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BMC Musculoskeletal Disorders, 2023 Background Benign peripheral nerve tumours consist of different types, most commonly Schwannomas. Preoperative Magnetic Resonance Imaging (MRI) is commonly performed before surgery and Pathoanatomical Diagnosis (PAD) confirms the diagnosis. Our aims were
Emanuel Istefan +3 more
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