Results 51 to 60 of about 94,200 (277)

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Prognostic Implications of Sleep Architecture for Patients Admitted to the Intensive Care Unit With Status Epilepticus

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Status epilepticus (SE) is associated with significant mortality. Sleep architecture may reflect normal brain function. Impaired sleep architecture is associated with poorer outcomes in numerous conditions. Here we investigate the association of sleep architecture in continuous EEG (cEEG) with survival in SE.
Ran R. Liu, Marcus C. Ng, Gavin P. Winston, Sabrina Schaly, Garima Shukla, Lysa Boissé Lomax   +5 more
wiley   +1 more source

Single-Cell RNA-Sequencing Shift in the Interaction Pattern Between Glioma Stem Cells and Immune Cells During Tumorigenesis

Frontiers in Immunology, 2020
Glioblastoma is one of the most common neoplasms in the central nervous system characterized by limited immune response and unlimited expansion capability.
You Zhai, Guanzhang Li, Renpeng Li, Yuanhao Chang, Yuemei Feng, Di Wang, Fan Wu, Wei Zhang, Wei Zhang, Wei Zhang   +9 more
doaj   +1 more source

Neonates with cancer and causes of death; lessons from 615 cases in the SEER databases [PDF]

, 2017
Neonatal tumors are rare with no standard treatment approaches to these diseases, and the patients experience poor outcomes. Our aim was to determine the distribution of cancers affecting neonates and compare survival between these cancers and older ...
Askin, Bresters, Buck, Drazen, Ferrari, Gigliotti, Isaacs, Isaacs, Isaacs, Isaacs, Johnson, Linden, Longo, Louis, Mili, Moore, Moore, Oi, Orbach, Parkes, Rankin, Roosen, Sande, Steliarova-Foucher, Thompson, Vormoor, Yu   +26 more
core   +1 more source

Spinal Cord Infarction Versus Idiopathic Transverse Myelitis: Clinical, Radiological, and Functional Insights From a Retrospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji, Jianlong Zhang, Yiming Shi, Shiyu Shan, Yang Du, Guangshuo Li, Ying Jin, Yani Zhang, Chuanying Wang, Yijun Lin, Yuhao Guo, Decai Tian, Xingquan Zhao, Tian Song   +13 more
wiley   +1 more source

Meningeal Carcinomatosis for Prostate Adenocarcinoma Mimicking Chronic Subdural Hematoma: Case Report and Literature Review

Brazilian Neurosurgery, 2021
Introduction Cerebral metastases are the most common cancer of the central nervous system (CNS). Meningeal infiltration by neoplasms that did not originate in the CNS is a rare fact that is present in 0.02% of the autopsies.
Tiago Silva Holanda Ferreira, Gilnard Caminha de Menezes Aguiar, Daniel Gurgel Fernandes Távora, Lucas Alverne Freitas de Albuquerque, Stélio da Conceição Araújo Filho   +4 more
doaj   +1 more source

Sympathoadrenergic modulation of hematopoiesis: a review of available evidence and of therapeutic perspectives [PDF]

, 2015
Innervation of the bone marrow (BM) has been described more than one century ago, however the first in vivo evidence that sympathoadrenergic fibers have a role in hematopoiesis dates back to less than 25 years ago.
Afan, Alexander, Arranz, Audus, Basu, Beaulieu, Beckman, Bell, Bellinger, Bellinger, Benarroch, Bencsics, Bergquist, Bhat, Bianco, Bjornsson, Byron, Cosentino, Cosentino, Cosentino, Cosentino, Cosentino, Cosentino, Cosentino, Cosentino, Cosentino, Cosentino, Courties, Dar, del Rey, Del Rio, DePace, Dygai, Elefteriou, Elenkov, Feldman, Felten, Felten, Felten, Ferrari, Flierl, Flierl, Franca Marino, Friedman, Frohman, Ganchev, Georges J. M. Maestroni, Giudice, Grisanti, Guasti, Hanoun, Heidt, Irwin, Izeku, Katayama, Kollet, Kuntz, Levite, Lipski, Lucas, Lymperi, Madden, Madden, Madden, Maestroni, Maestroni, Maestroni, Maestroni, Maestroni, Maestroni, Marazziti, Marco Cosentino, Marino, Marino, Marino, Marshall, Mendelson, Mladenovic, Morioka, Musso, Méndez-Ferrer, Nagatomi, Nance, Olechnowicz, Pacheco, Powell, Reguzzoni, Sarkar, Sarkar, Scheiermann, Schofield, Secker, Simmons, Sloan, Spiegel, Straub, Straub, Sun, Swanson, Templeton, Togni, Wang, Wrona, Yamazaki   +103 more
core   +2 more sources

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

Effect of Silybum Marianum on Reduction of Chemotherapy-Induced Peripheral Neurotoxicity with Cisplatin

Advanced Biomedical Research
Background: Chemotherapy-induced peripheral neurotoxicity (CIPN) is one of the major complications of chemotherapy regimens commonly used in the treatment of solid and hematologic cancers.
Ali Haji Gholami, Hourieh Ansari, Adeleh Dadkhah   +2 more
doaj   +1 more source

A Case of Cervical Intramedullary Dirofilaria immitis Associated with Nerve Sheath Tumor in a Dog [PDF]

Iranian Journal of Veterinary Surgery
Dirofilaria immitis, a globally widespread nematode known for its high mortality rate, primarily infests the cardiovascular system, notably the pulmonary artery and right ventricle.
Tohid Nasiribari, Zeynep Akçasız, Ebru Eravcı Yalın, Necati Öztürk, Damla Haktanır, Ahmet Gülçubuk   +5 more
doaj   +1 more source