Results 11 to 20 of about 1,526,105 (402)
Peripheral neuropathy in Parkinson’s disease: prevalence and functional impact on gait and balance
Brain : a journal of neurology, 2022 Peripheral neuropathy is a common problem in patients with Parkinson’s disease. Peripheral neuropathy’s prevalence in Parkinson’s disease varies between 4.8–55%, compared with 9% in the general population. It remains unclear whether peripheral neuropathy
M. Corrà +16 more
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Chemotherapy-Induced Peripheral Neuropathy: Epidemiology, Pathomechanisms and Treatment
Oncology and Therapy, 2021 This review provides an update on the current clinical, epidemiological and pathophysiological evidence alongside the diagnostic, prevention and treatment approach to chemotherapy-induced peripheral neuropathy (CIPN).
J. Burgess +10 more
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Blood biomarkers of peripheral neuropathy
Acta Neurologica Scandinavica, 2022 Traditionally, neurophysiology is the primary diagnostic and prognostic biomarker in peripheral neuropathy clinical practice; however, it may lack responsiveness in the context of slowly progressive neuropathies and where there is significant axonal ...
A. Rossor, M. Reilly
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Pathomechanisms of Paclitaxel-Induced Peripheral Neuropathy
Toxics, 2021 Peripheral neuropathy is one of the most common side effects of chemotherapy, affecting up to 60% of all cancer patients receiving chemotherapy. Moreover, paclitaxel induces neuropathy in up to 97% of all gynecological and urological cancer patients.
Ines Klein, H. Lehmann
semanticscholar +1 more source
Journal of Clinical Oncology, 2020 PURPOSE To update the ASCO guideline on the recommended prevention and treatment approaches in the management of chemotherapy-induced peripheral neuropathy (CIPN) in adult cancer survivors.
C. Loprinzi +15 more
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Frontiers in Pain Research, 2021 Painful diabetic peripheral neuropathy can be intractable with a major impact, yet the underlying pain mechanisms remain uncertain. A range of neuronal and vascular biomarkers was investigated in painful diabetic peripheral neuropathy (painful-DPN) and ...
Pallai Shillo +7 more
doaj +1 more source
Frontiers in Immunology, 2021 Peripheral neuropathies are characterized by nerves damage and axonal loss, and they could be classified in hereditary or acquired forms. Acquired peripheral neuropathies are associated with several causes, including toxic agent exposure, among which the
G. Fumagalli +4 more
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Inherited Peripheral Neuropathies [PDF]
Neurologic Clinics, 2013 Charcot-Marie-Tooth (CMT) disease is a heterogeneous group of inherited peripheral neuropathies in which the neuropathy is the sole or primary component of the disorder, as opposed to diseases in which the neuropathy is part of a more generalized neurologic or multisystem syndrome. Because of the great genetic heterogeneity of this condition, it can be
Mario A, Saporta, Michael E, Shy
openaire +4 more sources
Dabrafenib Promotes Schwann Cell Differentiation by Inhibition of the MEK-ERK Pathway
Molecules, 2021 Schwann cell differentiation involves a dynamic interaction of signaling cascades. However, much remains to be elucidated regarding the function of signaling molecules that differ depending on the context in which the molecules are engaged.
Kyuhee Park +4 more
doaj +1 more source
The integrated stress response contributes to tRNA synthetase–associated peripheral neuropathy
Science, 2021 Description Defeating peripheral neuropathy The mechanisms underlying peripheral neuropathies are not well understood. Spaulding et al. studied mouse models of the inherited Charcot-Marie-Tooth (CMT) disease, which is caused by mutations in transfer RNA (
E. Spaulding +22 more
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