Results 21 to 30 of about 697,317 (200)
The neuroinflammatory role of Schwann cells in disease
Neurobiology of Disease, 2013 Peripheral neuropathies are associated with a variety of clinical symptoms ranging from motor and sensory symptoms to autonomic dysfunction. The primary disease causes for peripheral nerve disorders are also very heterogeneous, including genetic causes ...
Elke Ydens +5 more
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Early-Onset of Transthyretin Amyloidosis in a Young Afro-Caribbean Woman With Thr60Ala Mutation
JACC: Case Reports, 2020 Transthyretin amyloidosis involves the deposition of transthyretin amyloid fibrils in the body. We report an unusual case of a young Afro-Caribbean woman harboring a Thr60Ala mutation who presented with clinical signs of heart failure and polyneuropathy ...
Stormy C. Keppel, MD +7 more
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HDAC6: A Key Link Between Mitochondria and Development of Peripheral Neuropathy
Frontiers in Molecular Neuroscience, 2021 Peripheral neuropathy, which is the result of nerve damage from lesions or disease, continues to be a major health concern due to the common manifestation of neuropathic pain. Most investigations into the development of peripheral neuropathy focus on key
Krystal English +3 more
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Transcriptional Fingerprint of Hypomyelination in and () Mice
ASN Neuro, 2016 The transcriptional program that controls oligodendrocyte maturation and central nervous system (CNS) myelination has not been fully characterized. In this study, we use high-throughput RNA sequencing to analyze how the loss of a key transcription factor,
Joshua D. Aaker +6 more
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Disease mechanisms in hereditary sensory and autonomic neuropathies
Neurobiology of Disease, 2006 Inherited peripheral neuropathies are common monogenically inherited diseases of the peripheral nervous system. In the most common variant, i.e., the hereditary motor and sensory neuropathies, both motor and sensory nerves are affected.
Nathalie Verpoorten +2 more
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Natural agents mediated autophagic signal networks in cancer
Cancer Cell International, 2017 Recent studies suggested that natural compounds are important in finding targets for cancer treatments. Autophagy (“self-eating”) plays important roles in multiple diseases and acts as a tumor suppressor in cancer.
Eun Jung Sohn, Hwan Tae Park
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Distal sensory polyneuropathy in HIV/TB co-infection : the role of vitamin B6 and N-acetyltransferase 2 genetic variation [PDF]
, 2012 Both human immunodeficiency virus (HIV) infection and tuberculosis (TB) are complicated by a painful distal sensory polyneuropathy (DSP) that may be due to virus-related HIV-DSP, antiretroviral toxic neuropathy (ATN) or isoniazid-induced peripheral ...
Centner, Chad
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Сахарный диабет, 2022 INTRODUCTION: The prevalence of diabetic foot syndrome is increasing in the Indian population. It is a triad of neurological, vascular, and biomechanical changes due to long term diabetes mellitus (DM).
H. Ya. Korada +5 more
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon +11 more
wiley +1 more source
Journal of Family Medicine and Primary Care, 2021 Introduction: Peripheral neuropathy is a common microvascular complication in patients with type 2 diabetes mellitus with a prevalence of around 50%. Objectives: This prospective observational cross-sectional study was done to assess serum calprotectin ...
Ramanathan Velayutham +3 more
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