Results 201 to 210 of about 1,472,414 (411)

MSSDA: Multi-Sub-Source Adaptation for Diabetic Foot Neuropathy Recognition [PDF]

open access: yesarXiv
Diabetic foot neuropathy (DFN) is a critical factor leading to diabetic foot ulcers, which is one of the most common and severe complications of diabetes mellitus (DM) and is associated with high risks of amputation and mortality. Despite its significance, existing datasets do not directly derive from plantar data and lack continuous, long-term foot ...
arxiv  

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia   +2 more
wiley   +1 more source

Assessment and management of diabetic ulcers in the primary health care setting [PDF]

open access: yes, 2008
John is a 62 year old gentleman who has been suffering from type 2 Diabetes Mellitus for the past 7 years. He presents to the clinic with an ulcer 5 mm in diameter on the lateral aspect of the right foot near the metatarsophalangeal joint area. The ulcer
De Gabriele, Renzo
core  

Delays in diagnosis and treatment of ATTR cardiac amyloidosis: A real‐world data analysis

open access: yesESC Heart Failure, EarlyView.
Abstract Aims and Background Cardiac amyloidosis leads to functional cardiac impairment and heart failure. Transthyretin amyloid cardiomyopathy (ATTR‐CM) is the most common form. After initial suspicion, diagnosis involves imaging techniques, biopsy and genetic tests, prompting transthyretin stabilizer therapy to slow disease progression.
Julia Vogel   +7 more
wiley   +1 more source

Charcot neuroarthropathy : pathogenesis, diagnosis and medical management [PDF]

open access: yes, 2008
Charcot neuroarthropathy (CN) is a progressive degenerative arthropathy which rarely complicates diabetes mellitus. Most commonly, though not exclusively affecting the foot, it seems to be determined by the interaction of neuropathy, osteopaenia and ...
Cachia, Mario J., Vella, Sandro
core  

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

open access: yesEnvironmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons   +17 more
wiley   +1 more source

Impact of foot progression angle modification on plantar loading in individuals with diabetes mellitus and peripheral neuropathy [PDF]

open access: yes, 2016
AIMS: To determine if participants can reduce foot progression angle (FPA), and if FPA reduction decreases regional plantar stresses and forces in individuals with diabetes.
Bohnert, Kathryn L   +5 more
core   +2 more sources

Genetic epilepsies with myoclonic seizures: Mechanisms and syndromes

open access: yesEpilepsia Open, EarlyView.
Abstract Genetic epilepsy with myoclonic seizures encompasses a heterogeneous spectrum of conditions, ranging from benign and self‐limiting forms to severe, progressive disorders. While their causes are diverse, a significant proportion stems from genetic abnormalities.
Antonietta Coppola   +3 more
wiley   +1 more source

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