Results 41 to 50 of about 1,526,105 (402)
MicroRNA 200c-3p regulates autophagy via upregulation of endoplasmic reticulum stress in PC-3 cells
Cancer Cell International, 2018 Background Autophagy is a response to cellular and environmental conditions and facilitates cell survival. Here, we investigated the role of ectopic expression of microRNA (miRNA) 200c-3p in autophagy. Methods miRNA mimics were used to overexpress miRNAs.
Eun Jung Sohn
doaj +1 more source
Early-Onset of Transthyretin Amyloidosis in a Young Afro-Caribbean Woman With Thr60Ala Mutation
JACC: Case Reports, 2020 Transthyretin amyloidosis involves the deposition of transthyretin amyloid fibrils in the body. We report an unusual case of a young Afro-Caribbean woman harboring a Thr60Ala mutation who presented with clinical signs of heart failure and polyneuropathy ...
Stormy C. Keppel, MD +7 more
doaj +1 more source
The neuroinflammatory role of Schwann cells in disease
Neurobiology of Disease, 2013 Peripheral neuropathies are associated with a variety of clinical symptoms ranging from motor and sensory symptoms to autonomic dysfunction. The primary disease causes for peripheral nerve disorders are also very heterogeneous, including genetic causes ...
Elke Ydens +5 more
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Mechanisms of Chemotherapy-Induced Peripheral Neuropathy
International Journal of Molecular Sciences, 2019 Chemotherapy-induced peripheral neuropathy (CIPN) is one of the most frequent side effects caused by antineoplastic agents, with a prevalence from 19% to over 85%.
R. Zajączkowska +5 more
semanticscholar +1 more source
Transcriptional Fingerprint of Hypomyelination in and () Mice
ASN Neuro, 2016 The transcriptional program that controls oligodendrocyte maturation and central nervous system (CNS) myelination has not been fully characterized. In this study, we use high-throughput RNA sequencing to analyze how the loss of a key transcription factor,
Joshua D. Aaker +6 more
doaj +1 more source
, 2014 Neurotoxicity refers to the direct or indirect effect of chemicals that disrupt the nervous system of humans or animals. Numerous chemicals can produce neurotoxic diseases in humans, and many more are used as experimental tools to disturb or damage the ...
Brust +15 more
core +2 more sources
Propylthiouracil and peripheral neuropathy [PDF]
Arquivos de Neuro-Psiquiatria, 1992 Peripheral neuropathy is a rare manifestation in hyperthyroidism. We describe the neurological manifestations of a 38 year old female with Graves' disease who developed peripheral neuropathy in the course of her treatment with propylthiouracil. After the drug was tapered off, the neurological signs disappeared.
Boekel, Valentina Van +6 more
openaire +5 more sources
Diagnosis of peripheral neuropathy
Neurological Research and Practice, 2020 Introduction Peripheral neuropathy represents a spectrum of diseases with different etiologies. The most common causes are diabetes, exposure to toxic substances including alcohol and chemotherapeutics, immune-mediated conditions, and gene mutations.
H. Lehmann +3 more
semanticscholar +1 more source
Disease mechanisms in hereditary sensory and autonomic neuropathies
Neurobiology of Disease, 2006 Inherited peripheral neuropathies are common monogenically inherited diseases of the peripheral nervous system. In the most common variant, i.e., the hereditary motor and sensory neuropathies, both motor and sensory nerves are affected.
Nathalie Verpoorten +2 more
doaj +1 more source
Glucose availability and sensitivity to anoxia of isolated rat peripheral nerve [PDF]
, 1991 The contrast between resistance to ischemia and ischemic lesions in peripheral nerves of diabetic patients was explored by in vitro experiments. Isolated and desheathed rat peroneal nerves were incubated in the following solutions with different glucose ...
DYCK P. J. +11 more
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