Results 71 to 80 of about 80,953 (281)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Vibrant: Virtual Brazilian Anthropology, 2017 This article looks to explore the analytic consequences of thinking about the urban peripheries of Rio de Janeiro not from the perspective of the city itself, capital of the State, but from the Baixada Fluminense, a cluster of cities in its Metropolitan ...
Carly Barboza Machado
doaj
Religions, 2015 To what extent and in what ways did the intellectual climate of Austria’s often ethnolinguistically heterogeneous borderlands contribute to the formation, institutionalization and diffusion of emerging social scientific discourses during the final ...
Thomas R. Prendergast
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, 1976 A braking apparatus is described for a tape transport device having two stacked coaxial reels and feelers mounted in proximity to the reels for sensing the tape being wound on each reel.
Carle, C. E.
core +1 more source
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
Queer Centres and Peripheries [PDF]
, 2013 Gradually queer theory, which emerged out of the particularities of academic and political situations in the USA in the 1990s, has begun to interrogate its relationship to the rest of the world.
Altman, Dennis
core +3 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Policing Vulnerable People in Island Contexts
International Journal for Crime, Justice and Social DemocracyThis special issue is dedicated to research that contributes to understanding, improving, and critiquing the policing of vulnerable people in island contexts. Democratic policing values emphasise a human rights approach that protects all persons equally.
Loene Howes, Wendell C Wallace
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FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source