Results 61 to 70 of about 26,622 (265)

Detecting TP53 mutations in paired liquid and tissue biopsies from patients with high‐grade serous ovarian carcinoma

International Journal of Cancer, EarlyView.
What's New? High‐grade serous ovarian carcinoma is often diagnosed at advanced stages due to non‐specific symptoms and the lack of reliable screening methods. This proof‐of‐concept study introduces a novel TP53 mutation panel using unique molecular identifier‐based next‐generation sequencing for sensitive detection of high‐grade serous ovarian ...
Amanda Olsson Widjaja, Peter Micallef, Maria Lycke, Tobias Österlund, Manuel Luna Santamaría, Julia Hedlund Lindberg, Therese Carlsson, Ulf Gyllensten, Anders Ståhlberg, Benjamin Ulfenborg, Anna Linder, Karin Sundfeldt   +11 more
wiley   +1 more source

2017 Update on Ovarian Cancer Peritoneal Carcinomatosis Multimodal-Treatment Considerations

Gastroenterology Research and Practice, 2018
Ovarian cancer peritoneal carcinomatosis requires a multimodal-treatment approach. Current treatment considerations are analyzed in this update and include the management of recurrent malignant ascites and the understanding of its pathophysiology, the ...
Evgenia Halkia, George Chrelias, Charalambos Chrelias, Jesus Esquivel   +3 more
doaj   +1 more source

Brazilian Society of Surgical Oncology: Guidelines and Consensus Statement for Palliative Surgery in Oncology

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background and Objective Palliative surgery in oncology aims to relieve symptoms, improve quality of life, and respect patient autonomy in advanced cancer. This study aimed to develop evidence‐based recommendations for safely indicating and performing palliative surgeries in Brazil, considering clinical, ethical, and multidisciplinary aspects.
Audrey Cabral Ferreira de Oliveira, Jordana Henz Hammes, Isabela Maria Alves de Almeida Oliva, Lara Andrade Mendes Mangieri, Ronald Enrique Delgado Bocanegra, Marcos Gonçalves Adriano Junior, Ana Caroline Fonseca Alves, Eliel Oliveira de Araujo, Jairo Cerqueira de Almeida Teixeira, Patricia Isabel Bahia Mendes Freire, Larissa de Jesus Almeida, Raquel Lacerda Dantas de Farias, Heládio Feitosa e Castro Neto, Alexandre Ferreira Oliveira, Reitan Ribeiro, Rodrigo Nascimento Pinheiro   +15 more
wiley   +1 more source

Peritoneal Carcinomatosis in Patients with Locally Advanced Colon Cancer: Literature Review

Российский журнал гастроэнтерологии, гепатологии, колопроктологии
Aim: to analyse and systematise available literature data on the diagnosis and treatment of patients with locally advanced colon cancer with peritoneal carcinomatosis.Key points.
S. Yu. Trishchenkov, O. V. Levina, V. M. Nekoval, V. V. Balaban, P. V. Tsarkov   +4 more
doaj   +1 more source

Prolonged Survival in a Patient with Neuroendocrine Tumor of the Cecum and Diffuse Peritoneal Carcinomatosis

Case Reports in Gastroenterology, 2012
Peritoneal carcinomatosis is a well-known factor of poor prognosis in patients with digestive adenocarcinomas. Peritoneal dissemination may also occur in midgut well-differentiated neuroendocrine tumors, but its influence on survival is ill-defined.
Louis de Mestier, Cindy Neuzillet, Olivia Hentic, Reza Kianmanesh, Pascal Hammel, Philippe Ruszniewski   +5 more
doaj   +1 more source

Hypoxia-inducible factor 1 alpha is required for the tumourigenic and aggressive phenotype associated with Rab25 expression in ovarian cancer [PDF]

, 2016
The small GTPase Rab25 has been functionally linked to tumour progression and aggressiveness in ovarian cancer and promotes invasion in three-dimensional environments.
Chalmers, Anthony J., Gomez-Roman, Natividad, McGregor, Fiona, Plumb, Jane   +3 more
core   +1 more source

Comparison of ultrasound with computed tomography and whole‐body diffusion‐weighted MRI in prediction of surgical outcome using ESMO‐ESGO criteria in patients with tubo‐ovarian carcinoma: prospective ISAAC study

Ultrasound in Obstetrics &Gynecology, EarlyView.
ABSTRACT Objective To test the non‐inferiority of extended abdominopelvic ultrasound examination compared with contrast‐enhanced computed tomography (CT) and whole‐body diffusion‐weighted magnetic resonance imaging (WB‐DWI/MRI) in discriminating preoperatively between resectable and non‐resectable disease based on the European Society for Medical ...
D. Fischerova, P. Pinto, J. L. Alcázar Zambrano, J. Vara‐Garcia, V. Chiappa, F. Raspagliesi, D. Franchi, A. V. Urbinati, A. C. Testa, J. Jarkovsky, D. Cibula, F. Moro, Collaborators, F. Frühauf, J. Slama, R. Kocian, S. Alessi, G. Avesani, K. Benesova, A. Burgetova, G. Calareso, L. Lambert, M. Masek, A. Fagotti, C. Panico, P. Pricolo, R. Vigorito   +26 more
wiley   +1 more source

The Many Faces of the Angry Peritoneum

Diagnostics
The peritoneum is a thin membrane that lines the abdominal cavity and covers the abdominal organs. It serves as a conduit for the spread of various pathological processes, including gas and fluid collections, inflammation, infections, and neoplastic ...
Maria Chiara Ambrosetti, Matilde Bariani, Giulia Angela Zamboni, Riccardo Valletta, Matteo Bonatti   +4 more
doaj   +1 more source

Magnetic Resonance Imaging of Peritoneal Carcinomatosis: Evaluation of High b-Value Computed Diffusion-Weighted Imaging

Current Oncology, 2022
Over the last few years, diffusion-weighted imaging (DWI) has become increasingly relevant in the diagnostic assessment of peritoneal carcinomatosis. The aim of this study was to investigate the benefits of high-b DWI (c-DWI) compared to standard DWI in ...
Maxime Ablefoni, Jakob Leonhardi, Constantin Ehrengut, Matthias Mehdorn, Robert Sucher, Ines Gockel, Timm Denecke, Hans-Jonas Meyer   +7 more
doaj   +1 more source

Comparative Outcomes of Reinforced Tension‐Line Sutures Versus Standard Closure Techniques in Patients Undergoing Laparotomy: A Systematic Review and Meta‐Analysis

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background The reinforced tension‐line suture (RTLS) technique distributes mechanical stress more evenly than traditional closure when closing a laparotomy wound, potentially reducing incisional hernia (IH) risk. We aimed to compare outcomes of RTLS versus standard closure techniques in patients undergoing laparotomy. Methods Systematic search
Rama H. G. Mikhail, Shahin Hajibandeh, Shahab Hajibandeh, Marty Smith, Ee Jun Ban, Rodney Jacobs, Siobhan C. McKay   +6 more
wiley   +1 more source