Results 71 to 80 of about 241,805 (307)

The molecular biology of peritoneal metastatic disease

EMBO Molecular Medicine, 2023
AbstractPeritoneal metastases are a common form of tumor cell dissemination in gastrointestinal malignancies. Peritoneal metastatic disease (PMD) is associated with severe morbidity and resistance to currently employed therapies. Given the distinct route of dissemination compared with distant organ metastases, and the unique microenvironment of the ...
Bootsma, Sanne, Bijlsma, Maarten F, Vermeulen, Louis   +2 more
openaire   +3 more sources

Effects of different peritoneal dialysis solutions on serum lipid levels and lipid profile in end-stage chronic kidney disease patients undergoing peritoneal dialysis

BMC Nephrology
Atherosclerotic cardiovascular diseases are the leading causes of morbidity and mortality in patients undergoing peritoneal dialysis and hemodialysis due to end-stage renal disease.
Gokhan Aydin, Cevat Topal, Kamil Konur, Oguzkan Ilmaz   +3 more
doaj   +1 more source

Characterization of human peritoneal monocyte/macrophage subsets in homeostasis: Phenotype, GATA6, phagocytic/oxidative activities and cytokines expression

Scientific Reports, 2018
Peritoneal macrophages play a critical role in the control of infectious and inflammatory diseases. Although recent progress on murine peritoneal macrophages has revealed multiple aspects on their origin and mechanisms involved in their maintenance in ...
Antonio José Ruiz-Alcaraz, Violeta Carmona-Martínez, María Tristán-Manzano, Francisco Machado-Linde, María Luisa Sánchez-Ferrer, Pilar García-Peñarrubia, María Martínez-Esparza   +6 more
doaj   +1 more source

Engineering Resatorvid‐Loaded Sub‐Microgels of Epigallocatechin‐3‐gallate/Hyaluronic Acid to Treat Acute Lung Injury

Advanced Healthcare Materials, EarlyView.
This study presents HAEP@Res sub‐microgels as a lung‐targeted delivery system integrating antioxidant activity with anti‐inflammatory therapy. The sub‐microgels demonstrate excellent biocompatibility, efficiently scavenge intracellular ROS, and downregulate pro‐inflammatory cytokines and genes in a Bleo‐induced ALI mouse model. These findings highlight
Bo Liu, Olawale Alimi Alimi, Benjamin Stearnes, Svetlana Romanova, Brady J. Sillman, Mena Asha Krishnan, Kristina Bailey, Benson J. Edagwa, Huanhuan Joyce Chen, Han‐jun Wang, Bin Duan   +10 more
wiley   +1 more source

Anti-Tumor Effects of TRAIL-Expressing Mesenchymal Stromal Cells in a Mouse Xenograft Model of Human Mesothelioma [PDF]

, 2015
Malignant mesothelioma (MM) remains a highly deadly malignancy with poor treatment option. The MM cells further promote a highly inflammatory microenvironment which contributes to tumor initiation, development, severity, and propagation. We reasoned that
Janes, SM, Sage, E
core  

Emotional management and biological markers of dietetic regimen in chronic kidney disease patients [PDF]

, 2016
The aim of the study was to investigate the association between psychological characteristics and biological markers of adherence in chronic kidney disease patients receiving conservative therapy, hemodialysis, peritoneal dialysis (PD), or kidney ...
Aceto, Paola, Berloco, Desiderata, Bruzzese, Vincenzo, Canulla, Francesco, Cesari, Valerio, Fazzari, Erika, Fortini, Antonio, Lai, Carlo, Lai, Silvia, Luciani, Massimiliano, Luciano, Stella   +10 more
core   +1 more source

Microengineered Gradient Hydrogels for Mechanobiology

Advanced Healthcare Materials, EarlyView.
Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong, Deepu Ashok, Anna Waterhouse, Marcela M. M. Bilek, Daniele Vigolo   +4 more
wiley   +1 more source

Malignant peritoneal mesothelioma in a woman with bilateral ovarian serous borderline tumour: Potential interactions between the two diseases

Gynecologic Oncology Reports, 2018
We report a case of a 59-year-old woman with peritoneal malignant mesothelioma and no previous exposure to asbestos with a diagnosis of bilateral ovarian serous borderline tumour with peritoneal implants one year before.
Lorena Losi, Laura Botticelli, Gianluca Taccagni, Ernesto Longinotti, Cesare Lancellotti, Letizia Scurani, Gian Franco Zannoni   +6 more
doaj   +1 more source

Dietary supplementation with fructooligosaccharides ameliorates allergy development following DEHP exposure in mice

Food and Agricultural Immunology, 2021
Fructooligosaccharides (FOS), a prebiotic supplement, can enhance immunological responses, probably through regulation of gastrointestinal microflora. On the other hand, some environmental pollutants have adjuvanticity against allergic reactions/diseases.
Akiko Yasuda, Ken-ichiro Inoue, Chiaki Sanbongi, Wakako Suzuki, Hirohisa Takano   +4 more
doaj   +1 more source

Caveolin-1 deficiency induces a MEK-ERK1/2-Snail-1-dependent epithelial-mesenchymal transition and fibrosis during peritoneal dialysis [PDF]

, 2015
Peritoneal dialysis (PD) is a form of renal replacement therapy whose repeated use can alter dialytic function through induction of epithelial-mesenchymal transition (EMT) and fibrosis, eventually leading to PD discontinuation. The peritoneum from Cav1-/-
Enrique, Calvo, Ignacio, Benedicto, Jesús, Loureiro, Jesús, Vázquez, Manuel López, Cabrera, Maria Teresa, Osteso, María Luisa Pérez, Lozano, Miguel Angel del, Pozo, Miguel, Foronda, Olga, Barreiro, Strippoli, Raffaele, Susana, Minguet, Teijo, Pellinen, Vanessa, Moreno   +13 more
core   +1 more source