Results 1 to 10 of about 408,139 (189)

The Gut-Peritoneum Axis in Peritoneal Dialysis and Peritoneal Fibrosis

Kidney Medicine, 2023
Peritoneal fibrosis is an important cause of peritoneal dialysis (PD) discontinuation worldwide and is associated with high morbidity and mortality rate.
Natalia Stepanova
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Peritoneal fibrosis: from pathophysiological mechanism to medicine [PDF]

Frontiers in Physiology
Peritoneal dialysis (PD) is currently one of the effective methods for treating end-stage renal disease (ESRD). However, long-term exposure to high concentration glucose in peritoneal dialysis environment could lead to peritoneal fibrosis (PF), impaired ...
Yingxi Kang, Yuan Liu, Ping Fu, Liang Ma
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Prevention and Treatment of Peritoneal Dialysis-Associated Fibrosis with Intraperitoneal Anti-Fibrotic Therapy in Experimental Peritoneal Fibrosis [PDF]

Pharmaceuticals
Background/Objectives: Long-term peritoneal dialysis (PD) often results in peritoneal damage and fibrosis, impairing peritoneal membrane function and leading to ultrafiltration failure.
Chiao-Yin Sun, Yu-Ting Hsieh, Shang-Chieh Lu, Chi-Ying F. Huang   +3 more
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Clinical and preclinical studies of mesenchymal stem cells to alleviate peritoneal fibrosis [PDF]

Stem Cell Research & Therapy
Peritoneal dialysis is an important part of end-stage kidney disease replacement therapy. However, prolonged peritoneal dialysis can result in peritoneal fibrosis and ultrafiltration failure, forcing patients to withdraw from peritoneal dialysis ...
Lingqian Zheng, Wenmin Chen, Kaijin Yao, Yina Xie, Chunling Liao, Tianbiao Zhou   +5 more
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Alteration of gut microbiota contributes to peritoneal fibrosis through increased production of trimethylamine N-oxide [PDF]

Gut Microbes
Peritoneal fibrosis is a common complication in peritoneal dialysis (PD) patients, which results in ultrafiltration failure (UFF) and PD withdrawal. PD patients demonstrate altered structural and functional profiles of the gut microbiota.
Weizhen Xie, Jiangzi Yuan, Chenhong Feng, Huinan Shi, Chenhong Zhang, Taofang Xi, Jiaying Huang, Wei Fang, Zhaohui Ni, Leyi Gu, Na Jiang   +10 more
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Extracellular vesicle‐packaged ILK from mesothelial cells promotes fibroblast activation in peritoneal fibrosis

Journal of Extracellular Vesicles, 2023
Progressive peritoneal fibrosis and the loss of peritoneal function often emerged in patients undergoing long‐term peritoneal dialysis (PD), resulting in PD therapy failure.
Qiang Huang, Yuxiang Sun, Long Peng, Juan Sun, Zixin Sha, Hongchun Lin, Yongjie Li, Canming Li, Huiqun Li, Hongli Shang, Yanxu Chen, Xianrui Dou, Zhaoyong Hu, Zengchun Ye, Hui Peng   +14 more
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Autophagy in peritoneal fibrosis [PDF]

Frontiers in Physiology, 2023
Peritoneal dialysis (PD) is a widely accepted renal replacement therapy for patients with end-stage renal disease (ESRD). Morphological and functional changes occur in the peritoneal membranes (PMs) of patients undergoing long-term PD.
Hong-yong Su, Jia-jie Yang, Rong Zou, Ning An, Xiao-cui Chen, Chen Yang, Hai-juan Yang, Cui-wei Yao, Hua-feng Liu   +8 more
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Integrating single-cell RNA-seq, bulk RNA-seq and network pharmacology reveals protective effect of salidroside in peritoneal dialysis-associated peritoneal fibrosis [PDF]

Frontiers in Pharmacology
Salidroside (2- (4-Hydroxyphenyl) ethyl β-D-glucopyranoside, SAL) is a bioactive compound present in Rhodiola rosea L., exhibiting diverse pharmacological properties such as anti-inflammatory and anti-fibrotic effects.
Shuting Li, Yue Ji, Silin Zhu, Mi Liu, Dan Luo, Qimei Luo, Min Mo, Haibo Long, Fenfen Peng, Zhanjun Jia, Xianrui Dou   +10 more
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Mechanisms underlying the involvement of peritoneal macrophages in the pathogenesis and novel therapeutic strategies for dialysis-induced peritoneal fibrosis [PDF]

Frontiers in Immunology
Long-term exposure of the peritoneum to peritoneal dialysate results in pathophysiological changes in the anatomical organization of the peritoneum and progressive development of peritoneal fibrosis.
Yangwei Wang, Yixian Zhang, Mingqi Ma, Xiaohua Zhuang, Yue Lu, Lining Miao, Xuehong Lu, Yingchun Cui, Wenpeng Cui   +8 more
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Galectin-1 and peritoneal fibrosis: a novel predictor for peritoneal metastasis in gastric cancer [PDF]

BMC Gastroenterology
Current indicators lack the precision required to accurately predict the PM(peritoneal metastasis) of gastric cancer (GC). The accurate prediction of GC with PM and the implementation of targeted therapeutic strategies hold substantial clinical ...
Chuanjiang Huang, Qingzhu Ding, Huina Wang, Zhiyi Cheng, Guiyuan Liu, Xiaolan You, Chungen Xing   +6 more
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