Results 21 to 30 of about 71,423 (312)

Brahma-related gene 1 acts as a profibrotic mediator and targeting it by micheliolide ameliorates peritoneal fibrosis [PDF]

Journal of Translational Medicine, 2023
Background Progressive peritoneal fibrosis is a worldwide public health concern impacting patients undergoing peritoneal dialysis (PD), yet there is no effective treatment.
Shuting Li, Congwei Luo, Sijia Chen, Yiyi Zhuang, Yue Ji, Yiqun Zeng, Yao Zeng, Xiaoyang He, Jing Xiao, Huizhen Wang, Xiaowen Chen, Haibo Long, Fenfen Peng   +12 more
doaj   +2 more sources

Extracellular vesicle‐packaged ILK from mesothelial cells promotes fibroblast activation in peritoneal fibrosis [PDF]

Journal of Extracellular Vesicles, 2023
Progressive peritoneal fibrosis and the loss of peritoneal function often emerged in patients undergoing long‐term peritoneal dialysis (PD), resulting in PD therapy failure.
Qiang Huang, Yuxiang Sun, Long Peng, Juan Sun, Zixin Sha, Hongchun Lin, Yongjie Li, Canming Li, Huiqun Li, Hongli Shang, Yanxu Chen, Xianrui Dou, Zhaoyong Hu, Zengchun Ye, Hui Peng   +14 more
doaj   +2 more sources

Zinc: a potential star for regulating peritoneal fibrosis [PDF]

Frontiers in Pharmacology
Peritoneal dialysis (PD) is a commonly used renal replacement therapy for patients with end-stage renal disease (ESRD). During PD, the peritoneum (PM), a semi-permeable membrane, is exposed to nonbiocompatible PD solutions. Peritonitis can occur, leading
Jian Li, Xinyang Li, Yangwei Wang, Lingfei Meng, Wenpeng Cui   +4 more
doaj   +2 more sources

Caffeic acid phenethyl ester restores mitochondrial homeostasis against peritoneal fibrosis induced by peritoneal dialysis through the AMPK/SIRT1 pathway [PDF]

Renal Failure
Increasing evidence suggests that peritoneal fibrosis induced by peritoneal dialysis (PD) is linked to oxidative stress. However, there are currently no effective interventions for peritoneal fibrosis.
Ying Lu, Luyan Gao, Wenwen Zhang, Ying Zeng, Ji Hu, Kai Song   +5 more
doaj   +2 more sources

Causes and mechanisms of peritoneal fibrosis and possible application of NF-κB inhibitor for prevention and treatment

Journal of Medical Science, 2019
Peritoneal dialysis is an established form of the renal replacement therapy in patients with end stage renal failure. Continuous Ambulatory Peritoneal Dialysis developed by Moncrief and Popovich in 1975 was a revolutionary event, and contributed much to ...
Andrzej Bręborowicz, Kazuo Umezawa
doaj   +3 more sources

Deletion of p38 MAPK in macrophages ameliorates peritoneal fibrosis and inflammation in peritoneal dialysis [PDF]

Scientific Reports
One of the most common causes of peritoneal dialysis withdrawal is ultrafiltration failure which is characterized by peritoneal membrane thickening and fibrosis.
Akie Ikushima, Takuya Ishimura, Keita P. Mori, Hiroyuki Yamada, Sayaka Sugioka, Akira Ishii, Naohiro Toda, Shoko Ohno, Yukiko Kato, Takaya Handa, Motoko Yanagita, Hideki Yokoi   +11 more
doaj   +2 more sources

Protein Arginine Methyltransferase 1-mediated Histone H4R3 Dimethyl Asymmetric enhances Epidermal Growth Factor Receptor signaling to promote Peritoneal Fibrosis. [PDF]

Int J Biol Sci
Chen H, Shi Y, Li J, Zhong Q, Ma X, Hu Y, Wang Y, Jiang D, Li X, Zhang S, Zhuang S, Liu N.   +11 more
europepmc   +3 more sources

Retracted: Sulodexide Prevents Peritoneal Fibrosis by Downregulating the Expression of TGF-β1 and Its Signaling Pathway Molecules. [PDF]

Evid Based Complement Alternat Med, 2023
And Alternative Medicine EC.
europepmc   +3 more sources

β-catenin initiates peritoneal fibrosis by triggering mitochondrial fission-mediated mesothelial cell senescence fate transition. [PDF]

Mil Med Res
Wang XX, Zhong WJ, Li JM, Wang D, Chen SQ, Miao JH, Shen WW, Li XL, Huang JW, Zhou S, Wang C, Ai J, Zhou LL.   +12 more
europepmc   +2 more sources

Therapeutic Potential of Oligo-Fucoidan in Mitigating Peritoneal Dialysis-Associated Fibrosis [PDF]

Marine Drugs
Peritoneal dialysis (PD) serves as a home-based kidney replacement therapy with increasing utilization across the globe. However, long-term use of high-glucose-based PD solution incites repeated peritoneal injury and inevitable peritoneal fibrosis, thus ...
Yu-Wei Chen, Mei-Yi Wu, Nai-Jen Huang, Mai-Szu Wu, Yung-Ho Hsu, Chia-Te Liao, Cheng-Hsien Chen   +6 more
doaj   +2 more sources