Results 31 to 40 of about 71,423 (312)

Pathogenesis of Peritoneal Fibrosis and Peritoneal Small Vessel Changes [PDF]

Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis, 1996
Masahiko Nakamoto
openalex   +3 more sources

Exosomes derived from bone marrow mesenchymal stem cells ameliorate peritoneal fibrosis induced by high glucose peritoneal dialysate solution in mice

陆军军医大学学报, 2022
Objective To investigate the role of exosomes derived from bone marrow mesenchymal stem cells (BMSCs) in peritoneal fibrosis induced by high glucose peritoneal dialysis in mice.
WANG Xiaoyue, AI Qingli, YU Fang, LUO Jia, WANG Liming   +4 more
doaj   +1 more source

Loss of JNK-Associated Leucine Zipper Protein Promotes Peritoneal Dialysis-Related Peritoneal Fibrosis

Kidney Diseases, 2022
Background: Peritoneal dialysis-related peritoneal fibrosis is the leading cause of peritoneal ultrafiltration failure. Multitude factors and pathological processes have been implicated in peritoneal fibrosis development and progression, whereas the ...
Maoqing Tian, Lu Zhang, Yujuan Wang, Meili Deng, Cancan Peng, Wei Liang, Guohua Ding, Bo Shen, Huiming Wang   +8 more
doaj   +1 more source

Ameliorative role of SIRT1 in peritoneal fibrosis: an in vivo and in vitro study

Cell & Bioscience, 2021
Background Peritoneal fibrosis is one of the major complications induced by peritoneal dialysis (PD). Damaged integrity and function of peritoneum caused by peritoneal fibrosis not only limits the curative efficacy of PD and but affects the prognosis of ...
Yanhong Guo, Liuwei Wang, Rong Gou, Yulin Wang, Xiujie Shi, Yage Zhang, Xinxin Pang, Lin Tang   +7 more
doaj   +1 more source

Suppression of Peritoneal Fibrosis by Sonoporation of Hepatocyte Growth Factor Gene-Encoding Plasmid DNA in Mice

Pharmaceutics, 2021
Gene therapy is expected to be used for the treatment of peritoneal fibrosis, which is a serious problem associated with long-term peritoneal dialysis. Hepatocyte growth factor (HGF) is a well-known anti-fibrotic gene.
Koyo Nishimura, Koki Ogawa, Maho Kawaguchi, Shintaro Fumoto, Hidefumi Mukai, Shigeru Kawakami   +5 more
doaj   +1 more source

Corrigendum: Apolipoprotein A-I attenuates peritoneal fibrosis associated with peritoneal dialysis by inhibiting oxidative stress and inflammation. [PDF]

Front Pharmacol
Lu J, Gao J, Sun J, Wang H, Sun H, Huang Q, Zhang Y, Zhong S.   +7 more
europepmc   +3 more sources

SIRT1-modified human umbilical cord mesenchymal stem cells ameliorate experimental peritoneal fibrosis by inhibiting the TGF-β/Smad3 pathway

Stem Cell Research & Therapy, 2020
Introduction Peritoneal fibrosis is a serious complication of long-term peritoneal dialysis (PD). Combination therapies are emerging as a promising treatment for tissue damage.
Yanhong Guo, Liuwei Wang, Rong Gou, Yulin Wang, Xiujie Shi, Xinxin Pang, Lin Tang   +6 more
doaj   +1 more source

Therapeutic mechanism of baicalein in peritoneal dialysis-associated peritoneal fibrosis based on network pharmacology and experimental validation

Frontiers in Pharmacology, 2023
Baicalein (5,6,7-trihydroxyflavone) is a traditional Chinese medicine with multiple pharmacological and biological activities including anti-inflammatory and anti-fibrotic effects.
Xiaohui Lu, Xiaohui Lu, Kefei Wu, Kefei Wu, Simin Jiang, Simin Jiang, Yi Li, Yi Li, Yating Wang, Yating Wang, Hongyu Li, Hongyu Li, Guanglan Li, Guanglan Li, Qinghua Liu, Qinghua Liu, Yi Zhou, Yi Zhou, Wei Chen, Wei Chen, Haiping Mao, Haiping Mao   +21 more
doaj   +1 more source

Preventing peritoneal membrane fibrosis in peritoneal dialysis patients [PDF]

Kidney International, 2016
Long-term peritoneal dialysis causes morphologic and functional changes in the peritoneal membrane. Although mesothelial-mesenchymal transition of peritoneal mesothelial cells is a key process leading to peritoneal fibrosis, and bioincompatible peritoneal dialysis solutions (glucose, glucose degradation products, and advanced glycation end products or ...
Qin, Zhou, M-Auxiliadora, Bajo, Gloria, Del Peso, Xueqing, Yu, Rafael, Selgas   +4 more
openaire   +2 more sources

Histone deacetylase 8 inhibition prevents the progression of peritoneal fibrosis by counteracting the epithelial-mesenchymal transition and blockade of M2 macrophage polarization

Frontiers in Immunology, 2023
BackgroundPeritoneal dialysis (PD) is an effective replacement therapy for end-stage renal disease patients. However, long-term exposure to peritoneal dialysate will lead to the development of peritoneal fibrosis.
Xun Zhou, Hui Chen, Yingfeng Shi, Jinqing Li, Xiaoyan Ma, Lin Du, Yan Hu, Min Tao, Qin Zhong, Danying Yan, Shougang Zhuang, Shougang Zhuang, Na Liu   +12 more
doaj   +1 more source