Results 51 to 60 of about 140,943 (327)

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Embryological, anatomical and clinical considerations on pleuroperitoneal communication

Pleura and Peritoneum, 2023
The pleural and peritoneal cavity share many related features due to their common celomic origin. Normally these two spaces are completely separated with the development of the diaphragm.
Chatzigrigoriadis Christodoulos, Goulioumis Anastasios, Sperdouli Despoina, Gyftopoulos Kostis   +3 more
doaj   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

Cutaneous melanoma in older patients

BMC Geriatrics
Background In industrialized countries, the aging population is steadily rising. The incidence of cutaneous malignant melanoma (CMM) is highest in old people.
Alessandra Buja, Massimo Rugge, Chiara Trevisiol, Anna Zanovello, Alessandra Rosalba Brazzale, Manuel Zorzi, Antonella Vecchiato, Paolo Del Fiore, Saveria Tropea, Marco Rastrelli, Carlo Riccardo Rossi, Simone Mocellin   +11 more
doaj   +1 more source

Germanane Quantum Dots Promote Metabolic Reprogramming of Immune Cells Toward Regulatory T Cells and Suppress Inflammation In Vitro and In Vivo

Advanced Functional Materials, EarlyView.
Metabolic changes in immune cells direct the phenotype and function of the host immune system. Smart nanomaterials must target metabolic pathways to direct immune cell fate. This study reports the fabrication and first application of germanane quantum dots (GeHQDs) to modulate inflammation in vitro and in vivo.
Abhay Srivastava, Alireza Rafieerad, Weiang Yan, Keshav Narayan Alagarsamy, Qingdong Guan, Leena Regi Saleth, Michel Aliani, Sanjiv Dhingra   +7 more
wiley   +1 more source

Diagnostic challenges and importance of early multidisciplinary intervention in acral melanoma: a case report

Dermatology Reports
Acral melanoma (AM) is a rare subtype of melanoma that occurs on acral sites such as the palms, soles, and subungual regions. Due to its atypical presentation and frequent lack of pigmentation in the amelanotic variant (AAM), diagnosis is often delayed ...
Fortunato Cassalia, Paolo Del Fiore, Andrea Danese, Michele Soldà, Vincenzo Furfaro, Simone Mocellin   +5 more
doaj   +1 more source

Peritoneal splenosis mimicking carcinomatosis

The Pan African Medical Journal, 2016
Splenosis is an uncommon benign condition resulting from heterotopic autotransplantation of splenic tissues onto exposed vascularised intra- and extraperitoneal surfaces following splenic trauma and surgeries. Splenosis may be mistaken for carcinomatosis
Faten Limaiem, Rahma Ayadi, Ghada Sahraoui, Saadia Bouraoui, Ahlem Lahmar, Sabeh Mzabi   +5 more
doaj   +1 more source

Immunohistochemical study of pathological alterations of peritoneum in patients with terminal renal insufficiency and on peritoneal dialysis [PDF]

Vojnosanitetski Pregled, 2011
Background/Aim. During peritoneal dialysis (PD) an exchange of substances between blood and dialysate takes place through specific histological structures of peritoneum.
Trbojević-Stanković Jasna, Obradović Miljana, Čemerikić-Martinović Vesna, Trpinac Dušan, Laušević Željko, Stojimirović Biljana   +5 more
doaj   +1 more source

Isolation of Mature (Peritoneum-Derived) Mast Cells and Immature (Bone Marrow-Derived) Mast Cell Precursors from Mice

PLoS ONE, 2016
Mast cells (MCs) are a versatile cell type playing key roles in tissue morphogenesis and host defence against bacteria and parasites. Furthermore, they can enhance immunological danger signals and are implicated in inflammatory disorders like fibrosis ...
Steffen K. Meurer, M. Neß, S. Weiskirchen, P. Kim, C. Tag, Marlies Kauffmann, M. Huber, R. Weiskirchen   +7 more
semanticscholar   +1 more source

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source