Results 171 to 180 of about 5,273,568 (326)

Giant tumefactive perivascular spaces [PDF]

open access: yes, 2005
Background and purpose: The brain perivascular spaces (PVSs) are pial-lined, interstitial fluid-filled structures that accompany penetrating arteries.
House, Paul   +6 more
core  

Editorial: Enlarged perivascular spaces: etiology and significance

open access: yesFrontiers in Neuroscience, 2023
Michele Cavallari   +3 more
doaj   +1 more source

Heparan sulfate and glycomimetics: Advances in synthesis and biological applications for post‐stroke neurorepair

open access: yesNeuroprotection, EarlyView.
ECM, extracellular matrix; BDNF, brain‐derived neuroptrophic factor; FGF, fibroblast growth factor; VEGF, vascular endothelial growth factor. Abstract Heparan sulfate, a structurally diverse glycosaminoglycan that is abundant in the central nervous system (CNS), orchestrates essential processes fundamental to neural plasticity, neurorepair, and ...
Mozammel H. Bhuiyan   +3 more
wiley   +1 more source

Quantity and Volume of Perivascular Spaces Are Inversely Associated With Multiple Sclerosis Relative to Cerebrovascular Disease and Migraine

open access: yesAnnals of Clinical and Translational Neurology
Objective To quantify the number and volume of whole brain perivascular spaces (PVS) using a detection and segmentation algorithm in participants with multiple sclerosis (MS) and patients with disorders mimicking MS known to potentially influence PVS ...
Elle M. Levit   +5 more
doaj   +1 more source

Immune dysregulation in the prostates of C57BL/6Aire−/− mice mirrors that seen in human benign prostatic hyperplasia

open access: yesThe Journal of Pathology, EarlyView.
Abstract Benign prostatic hyperplasia (BPH) is the most common urologic disease in aging men, resulting in significant morbidity. The etiologies of BPH are unknown, though chronic prostatic inflammation is known to promote hyperplasia, fibrotic remodeling, and therapeutic resistance in BPH.
Nadia A Lanman   +12 more
wiley   +1 more source

Human Blood‐Brain Tumor Barrier on a Chip to Investigate Personalized Treatment for Glioblastoma Patients

open access: yesSmall, EarlyView.
A microfluidic model of the glioblastoma (GBM) margin was developed to mimic patient‐specific blood‐brain tumor barrier (BBTB) function and drug response. The platform revealed inter‐patient variability in barrier integrity and drug sensitivity, offering a tool for personalized therapy evaluation in GBM.
Minsu Ryoo   +16 more
wiley   +1 more source

Advances in deep‐tissue fluorescence imaging through optical clearing: A review

open access: yesVIEW, EarlyView.
Optical clearing refers to techniques that are used to improve the optical transparency of biological tissues. Optical clearing enables imaging of deeper lying tissues as well as 3D volumetric imaging of whole organs. This review examines reports on the integration of optical clearing with advanced fluorescence imaging techniques, with particular ...
Alaka Pramod   +4 more
wiley   +1 more source

Biomarkers Predictive of Immunotherapy Efficacy in Head and Neck Squamous Cell Carcinoma: Current Insights and Future Perspectives

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT With the approval of immunotherapies by regulatory bodies, head and neck squamous cell carcinoma (HNSCC) treatment has been revolutionized, and anti‐programmed cell death‐1 (anti‐PD‐1) agents are now the standard for platinum‐resistant recurrent/metastatic HNSCC.
Xiao‐Tong Yan   +2 more
wiley   +1 more source

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