Results 71 to 80 of about 3,550,881 (351)

Emancipated Youth Connections Project Final Report/Toolkit [PDF]

, 2007
This report presents findings and recommendations from the Emancipated Youth Connections Project, a model program designed to seek and sustain permanent lifelong connections for older youth who have already emancipated from foster care without a ...
Cheryl J. Jacobson
core  

Monotone Projection Lower Bounds from Extended Formulation Lower Bounds [PDF]

, 2017
In this short note, we reduce lower bounds on monotone projections of polynomials to lower bounds on extended formulations of polytopes. Applying our reduction to the seminal extended formulation lower bounds of Fiorini, Massar, Pokutta, Tiwari, & de ...
Grochow, Joshua A.
core   +3 more sources

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Comparative Evaluation of the Marginal Sealing Ability of two Commercially Available Pit and Fissure Sealants [PDF]

Journal of Clinical and Diagnostic Research, 2016
Introduction: The occlusal surfaces of the teeth usually have pits and fissures which provide a good environment for demineralization with minimal salivary access and make them caries prone.
Lakshmi Priya Sridhar, Joyson Moses, Bollam Nammalwar Rangeeth, Subramanian Sivakumar   +3 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Comparitive study of the influence of harmonic voltage distortion on the efficiency of induction machines versus line start permanent magnet machines [PDF]

, 2012
Induction machines have nearly reached their maximal efficiency. In order to further increase the efficiency the use of permanent magnets in combination with the robust design of the induction machine is being extensively researched. These so-called line
Debruyne, Colin, Derammelaere, Stijn, Desmet, Jan, Vandevelde, Lieven   +3 more
core  

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Magnetic nanowires as permanent magnet materials

, 2007
We present the fabrication of metallic magnetic nanowires using a low temperature chemical process. We show that pressed powders and magnetically oriented samples exhibit a very high coercivity (6.5 kOe at 140 K and 4.8 kOe at 300 K).
Craik D. J., F. Ott, G. Chaboussant, G. Viau, J.-Y. Piquemal, T. Maurer, Y. Soumare   +6 more
core   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source