Results 71 to 80 of about 1,497,536 (354)
A Systematic Review on the Risk Factors of Congenital Hypothyroidism
Journal of Pediatrics Review, 2019 Context: Congenital Hypothyroidism (CH) is the most common endocrine disorder and causes of preventable mental retardation in children. Objective: We aimed to review the reported CH-related risk factors systematically.
Mahin Hashemipour +4 more
doaj
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Accurate Detection of Non-Cavitated Proximal Caries in Posterior Permanent Teeth: An in vivo Study
Risk Management and Healthcare Policy, 2020 Raghad Alammar,1 Durre Sadaf2,3 1Qassim University, College of Dentistry, Buraidah, Alqassim, Saudi Arabia; 2Conservative Dentistry Department, Qassim University, College of Dentistry, Buraidah, Alqassim, Saudi Arabia; 3University of Oxford, Centre for ...
Alammar R, Sadaf D
doaj
Generalized matrix functions, determinant and permanent
پژوهشهای ریاضی, 2022 Introduction Since linear and multilinear algebra has many applications in different branches of sciences, the attention of many mathematicians has been attracted to it in recent decades. The determinant and the permanent are the most important functions
Mohammad Hossein Jafari, Ali Reza Madadi
doaj
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
FEBS Letters, EarlyView.We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Journal of Indian Association of Public Health Dentistry, 2020 Background: Tooth eruption is influenced by various factors which include physiological and genetic factors. The first permanent teeth to erupt are the permanent first molars at the age of 6 years.
Priya Subramaniam, Raksha Pagadala
doaj +1 more source
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source