Results 81 to 90 of about 1,497,536 (354)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Traumatic dental injuries among children attending the public after-hours emergency dental clinic in Bergen, Norway

Acta Odontologica Scandinavica
Objectives: To investigate traumatic dental injuries (TDIs) among children who for 1 year attended a Norwegian public after-hours emergency public dental (EPD) clinic. Materials and methods: The study included 7–18-year-olds (n = 312) who presented at
Faiza D. Sælen, Jorma I. Virtanen, Marit S. Skeie, Gerhard Sulo, Dorina S. Thelen   +4 more
doaj   +1 more source

MnBi thin films for high temperature permanent magnet applications

AIP Advances, 2019
Thin films of ferromagnetic LTP-MnBi (Low Temperature Phase of MnBi) have been grown by magnetron sputtering onto quartz substrates. Two particular issues related to LTP-MnBi have been investigated: the strong influence of the growth temperature and the ...
M. Villanueva, C. Navío, E. Céspedes, F. Mompeán, M. García-Hernández, J. Camarero, A. Bollero   +6 more
doaj   +1 more source

Agenesis of permanent canines: Rare case report

Dental Research Journal, 2017
Agenesis of permanent canines is a rare condition, and that of both maxillary and mandibular permanent canines is extremely rare. It may occur either isolated or in association with other dental anomalies.
Sumit Kumar Yadav, Achla Bharti Yadav, Neal Bharat Kedia, Abhinav Kumar Singh   +3 more
doaj   +1 more source

Perspectives for high-performance permanent magnets: applications, coercivity, and new materials

, 2017
High-performance permanent magnets are indispensable in the production of high-efficiency motors and generators and ultimately for sustaining the green earth.
S. Hirosawa, M. Nishino, S. Miyashita
semanticscholar   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Management of early loss of first permanent molar: A new technique

Journal of Indian Society of Pedodontics and Preventive Dentistry, 2012
The loss of a permanent first molar in adolescent patient creates a need for early space maintenance and restoration of function. To ascertain function and esthetics, immediate treatments include interim restorative approaches.
B S Rajashekhara, J M Keyur, D Bhavna, K S Poonacha   +3 more
doaj   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Lithosphere delamination with foundering of lower crust and mantle caused permanent subsidence of New Caledonia Trough and transient uplift of Lord Howe Rise during Eocene and Oligocene initiation of Tonga-Kermadec subduction, western Pacific [PDF]

, 2010
Rupert Sutherland, Julien Collot, Y. Lafoy, Graham A. Logan, Ron Hackney, Vaughan Stagpoole, Chris Uruski, Takehiko Hashimoto, Karen Higgins, Richard H. Herzer, Ray Wood, N. Mortimer, Nadège Rollet   +12 more
openalex   +1 more source