Results 241 to 250 of about 279,150 (304)

Cigarette Smoke‐Induced Alveolar Macrophage Senescence via GEM/SIRT3‐Mediated Mitochondrial Dysfunction

Advanced Science, EarlyView.
Cigarette smoke accelerates the aging of immune cells in the lung. By combining human single‐cell sequencing, cell culture, and mouse models, the authors show that the protein GEM drives mitochondrial damage and senescence in alveolar macrophages by suppressing SIRT3.
Jin Wang, Meidan Wei, Xiangrong Song, Jiaxin Zhang, Lisha Zhang, Sixian Chen, Yaoyu Hu, Hui Gao, Jianxiang Li   +8 more
wiley   +1 more source

Passive nuclear transport deviates from Fickian behavior in prostate and breast cell types. [PDF]

Nucleus
Scott NR, Lin AJ, Belardi B, Parekh SH.
europepmc   +1 more source

Mitochondrial Functional Capacity Is Impaired in Angiotensin II-Infused Mice and Not Recovered by Metformin. [PDF]

Biomedicines
Balboa Ramilo A, Mani K, Wanhainen A, Friederich-Persson M, Wågsäter D.   +4 more
europepmc   +1 more source

Oncogenic receptor tyrosine kinase signaling is driven by the Golgi protein GOLPH3 and its interaction with MYO18A. [PDF]

Sci Signal
Starost KA, Bommi JR, Peterman MC, McCullough MX, Buschman MD, Yun B, Field SJ.   +6 more
europepmc   +1 more source

A Syndecan-Based Genetic Approach to Coat the Surface of Small Extracellular Vesicles With Nanobodies. [PDF]

J Extracell Biol
Hyka L, Meeussen S, Ghossoub R, De Coster M, De Bruyne E, David G, Chames P, Zimmermann P.   +7 more
europepmc   +1 more source

Flow cytometry method to identify arginase-1 expressing MDSCs. [PDF]

MethodsX
Srinivasan P, Bechtel M, Wyczechowska D, Ochoa AC, Fisch MJ, Henry NL, Unger JM, Hamilton-Reeves JM.   +7 more
europepmc   +1 more source

Valproic Acid Stimulates Release of Ca²⁺ from InsP₃-Sensitive Ca²⁺ Stores. [PDF]

Int J Mol Sci
Ruiz-Nuño A, Cano-Abad MF.
europepmc   +1 more source

Further Characterization of Dopamine Release by Permeabilized PC 12 Cells [PDF]

Journal of Neurochemistry, 1987
Rat pheochromocytoma cells (PC 12) permeabilized with staphylococcal α-toxin release [3H]dopamine after addition of micromolar Ca2+. This does not require additional Mg2+-ATP (in contrast to bovine adrenal medullary chromaffin cells).
G Ahnert-Hilger
exaly   +2 more sources

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Bioconversions in Permeabilized Cells

2021
Whole cells made permeable by chemical or physical treatment allow the conversion of substrates to useful, expensive products. Permeabilized cells are useful if substrate or product or both cannot enter the cell. As many commercially interesting bioconversions require cofactor-dependent enzymes, regeneration of expensive cofactors is necessary. This is
openaire   +2 more sources

Fixation and Permeabilization of Cells and Tissues

Cold Spring Harbor Protocols, 2008
INTRODUCTIONFluorescence microscopy is used to visualize specific cellular components in as native a state and organization as possible. This article describes some of the main issues that must be considered when cells and tissues are fixed and permeabilized. To preserve cellular structure, the specimen is fixed chemically to retain the cells or tissue
Fischer, Andrew H., Jacobson, Kenneth A., Rose, Jack, Zeller, Rolf   +3 more
openaire   +2 more sources