Results 41 to 50 of about 285,928 (326)
Development of a Nanoemulgel for the Topical Application of Mupirocin
Pharmaceutics, 2023 Mupirocin (MUP) is an effective topical antibiotic with poor skin permeability; however, its skin permeability can be improved by a nanoemulsion formulation based on eucalyptus oil or eucalyptol. Despite this improvement, the nanoemulsion has limitations,
Bahjat Alhasso +3 more
doaj +1 more source
Proton block of proton-activated TRPV1 current. [PDF]
, 2015 The TRPV1 cation channel is a polymodal nociceptor that is activated by heat and ligands such as capsaicin and is highly sensitive to changes in extracellular pH. In the body core, where temperature is usually stable and capsaicin is normally absent, H(+)
Lee, Bo Hyun, Zheng, Jie
core +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Fucoxanthin-Containing Cream Prevents Epidermal Hyperplasia and UVB-Induced Skin Erythema in Mice [PDF]
, 2018 Microalgae represent a source of bio-active compounds such as carotenoids with potent anti-inflammatory and antioxidant properties. We aimed to investigate the effects of fucoxanthin (FX) in both in vitro and in vivo skin models.
Cózar Bernal, María José +6 more
core +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Oxygen permeation through oxygen ion oxide-noble metal dual phase composites [PDF]
, 1996 Oxygen permeation behaviour of three composites, yttria-stabilized zirconia-palladium, erbia-stabilized bismuth oxidenoble metal (silver, gold) was studied.
Bouwmeester, H.J.M. +4 more
core +2 more sources
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Journal of Experimental Nanoscience, 2017 Nanofibres of TiO2 were synthesised by hydrothermal routine. Cellulose acetate/TiO2 nanofibre composite membranes were synthesised via blending TiO2 nanofibre in cellulose acetate solutions in 1-methyl-2-pyrrolidone.
Satya Deepika Neelapala +2 more
doaj +1 more source
Design and development of cefdinir niosomes for oral delivery
Journal of Pharmacy and Bioallied Sciences, 2013 Objective: The aim of the present study was to develop nonionic surfactant based vesicles (niosomes) to improve poor and variable oral bioavailability of cefdinir.
Saurabh Bansal +3 more
doaj +1 more source
Improvement of a method for the characterization of ultrafiltration membranes by measurements of tracers retention [PDF]
, 2004 The aim of this study is to improve protocols for assessing accurate characteristic retention curve and cut-off of membranes, thus enabling the manufacture and performance of the membrane to be monitored. Different data treatments are considered in order
Aimar, Pierre +3 more
core +2 more sources