Results 21 to 30 of about 168,330 (260)

Development of Nanoemulsions for Topical Application of Mupirocin

open access: yesPharmaceutics, 2023
Mupirocin (MUP) is a topical antibacterial agent used to treat superficial skin infections but has limited application due to in vivo inactivation and plasma protein binding.
Bahjat Alhasso   +2 more
doaj   +1 more source

Tailored nanostructured platforms for boosting transcorneal permeation: Box–Behnken statistical optimization, comprehensive in vitro, ex vivo and in vivo characterization [PDF]

open access: yes, 2017
Ibrahim Elsayed,1,2 Sinar Sayed1 1Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University, Cairo, Egypt; 2Department of Pharmaceutical Sciences, College of Pharmacy, Gulf Medical University, Ajman, United Arab Emirates
Elsayed I   +3 more
core   +1 more source

Cannabidiol-Loaded Nanostructured Lipid Carriers (NLCs) for Dermal Delivery: Enhancement of Photostability, Cell Viability, and Anti-Inflammatory Activity

open access: yesPharmaceutics, 2023
The aim of this study was to encapsulate cannabidiol (CBD) extract in nanostructured lipid carriers (NLCs) to improve the chemical stability and anti-inflammatory activity of CBD for dermal delivery.
Boontida Morakul   +3 more
doaj   +1 more source

Effect of Environmental Gas on Surface Initiated Rolling Contact Fatigue

open access: yesTribology Online, 2013
This paper describes an exploratory study on the effects of temperature on the formation of oxide film and rolling contact fatigue life in hydrogen, argon and air.
Hiroyoshi Tanaka   +4 more
doaj   +1 more source

The Vaginal-PVPA: A Vaginal Mucosa-Mimicking In Vitro Permeation Tool for Evaluation of Mucoadhesive Formulations

open access: yesPharmaceutics, 2020
Drug administration to the vaginal site has gained increasing attention in past decades, highlighting the need for reliable in vitro methods to assess the performance of novel formulations.
Margherita Falavigna   +5 more
doaj   +1 more source

A Model to Simulate Gas Dissolution into/through Metals and Its Application to Deuterium in a 316L Steel Chamber with Pb-Li in a Quasi-2D Geometry

open access: yesApplied Sciences, 2022
Liquid lead-lithium in eutectic proportions (Pb-Li) is a candidate material for Breeding Blankets (BBs) in future Fusion Power Plants (FPP). BB design depends on the diffusivity and Sieverts’ constant (solubility) of tritium in this alloy, but literature
Tiago Pomella Lobo   +2 more
doaj   +1 more source

Investigation of Permeation of Theophylline through Skin Using Selected Piperazine-2,5-Diones

open access: yesMolecules, 2019
Transdermal administration of drugs that penetrate, in this case directly into the blood circulation, has many advantages and is promising for many drugs thanks to its easy application and good patient compliance.
Aneta Pokorna   +5 more
doaj   +1 more source

The Permeation Mechanism of Cisplatin Through a Dioleoylphosphocholine Bilayer** [PDF]

open access: yes, 2021
The investigation of the intermolecular interactions between platinum-based anticancer drugs and lipid bilayers is of special relevance to unveil the mechanisms involved in different steps of the anticancer mode of action of these drugs.
Nogueira, Juan J.   +8 more
core   +2 more sources

Permeation-Enhanced Degassing Method Based on Xylem Embolism Repair and Gas Permeable Materials

open access: yes
Microfluidic devices have developed a wide range of applications in the fields of biomedicine, chemistry, and analytical science. But it is easy to form and accumulate bubbles in microfluidic devices.
Shuqing Yin (13877366)   +5 more
core   +4 more sources

Optimization of experimental conditions for skin-PAMPA measurements

open access: yesADMET and DMPK, 2020
In recent years, the parallel artificial membrane permeability assay (PAMPA) has been extended for prediction of skin permeation by developing an artificial membrane which mimics the stratum corneum structure, skin-PAMPA.
Sara Soriano-Meseguer   +3 more
doaj   +1 more source

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