Results 21 to 30 of about 97,006 (262)

Optimization of experimental conditions for skin-PAMPA measurements

ADMET and DMPK, 2020
In recent years, the parallel artificial membrane permeability assay (PAMPA) has been extended for prediction of skin permeation by developing an artificial membrane which mimics the stratum corneum structure, skin-PAMPA.
Sara Soriano-Meseguer, Elisabet Fuguet, Adriana Port, Martí Rosés   +3 more
doaj   +1 more source

Fabrication and function of polymer membranes

Chemistry Teacher International, 2021
The paper gives an introduction to membrane science and technology, an area of research of high significance for the development of a sustainable life for human beings.
Abetz Volker, Brinkmann Torsten, Sözbilir Mustafa   +2 more
doaj   +1 more source

On Diffusion and Permeation

Journal of Non-Equilibrium Thermodynamics, 2009
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +4 more sources

Diclofenac Salts, VIII. Effect of the Counterions on the Permeation through Porcine Membrane from Aqueous Saturated Solutions

Pharmaceutics, 2012
The following bases: monoethylamine (EtA), diethylamine (DEtA), triethylamine (TEtA), monoethanolamine (MEA), diethanolamine (DEA), triethanolamine (TEA), pyrrolidine (Py), piperidine (Pp), morpholine (M), piperazine (Pz) and their N-2-hydroxyethyl (HE ...
Cristina Cavallari, Annamaria Monastero, Glenda Bassini, Adamo Fini   +3 more
doaj   +1 more source

Design of a nanostructured mucoadhesive system containing curcumin for buccal application: from physicochemical to biological aspects

Beilstein Journal of Nanotechnology, 2019
Mucoadhesive nanostructured systems comprising poloxamer 407 and Carbopol 974P® have already demonstrated good mucoadhesion, as well as improved mechanical and rheological properties.
Sabrina Barbosa de Souza Ferreira, Gustavo Braga, Évelin Lemos Oliveira, Jéssica Bassi da Silva, Hélen Cássia Rosseto, Lidiane Vizioli de Castro Hoshino, Mauro Luciano Baesso, Wilker Caetano, Craig Murdoch, Helen Elizabeth Colley, Marcos Luciano Bruschi   +10 more
doaj   +1 more source

Effectiveness of polymeric gloves in radioprotection against contamination in nuclear medicine

Brazilian Journal of Radiation Sciences, 2023
When handling unsealed radioactive sources, radiological protection attention must be taken to avoid unnecessary exposure and radioactive contaminations, and an important and necessary practice to prevent such contaminations is the use of gloves when ...
Leonardo Pessoa da Silva, Josiane Bueno Salazar, Andréia Caroline Fischer da Silveira Fischer, Fernanda Ramos de Oliveira, Fernanda Chiarello Stedile   +4 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Progress and Prospects in Permeation [PDF]

The Journal of General Physiology, 1999
Many laboratories study the movement of ions through single channel molecules every day using the dazzling techniques of molecular and membrane biology. Atomic details of a channel are changed and the correlations of structure and function are observed routinely, but the correlations have ...
W, Nonner, D P, Chen, B, Eisenberg
openaire   +2 more sources

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Development of a Nanoemulgel for the Topical Application of Mupirocin

Pharmaceutics, 2023
Mupirocin (MUP) is an effective topical antibiotic with poor skin permeability; however, its skin permeability can be improved by a nanoemulsion formulation based on eucalyptus oil or eucalyptol. Despite this improvement, the nanoemulsion has limitations,
Bahjat Alhasso, Muhammad Usman Ghori, Simon P. Rout, Barbara R. Conway   +3 more
doaj   +1 more source