Results 11 to 20 of about 168,330 (260)

Liposomal co-permeation assay reveals unexpected membrane interactions of commonly prescribed drugs [PDF]

open access: yes, 2023
The permeation of small molecules across biological membranes is a crucial process that lies at the essence of life. Permeation is involved not only in the maintenance of homeostasis at the cell level but also in the absorption and biodistribution of ...
Martin, Balouch   +5 more
core   +1 more source

jacopofrallicciardi/Small-Molecule-Permeation: Determining small molecule permeation through lipid membranes-Scripts

open access: yes, 2022
Set of scripts (MATLAB) for the data analysis of small molecules permeation through biological membranes both in vitro and in ...
jacopofrallicciardi
core   +1 more source

The Effect of Temperature, Sulfonation, and PEG Addition on Physicochemical Characteristics of PVDF Membranes and Its Application on Hemodialysis Membrane

open access: yesIndonesian Journal of Chemistry, 2021
Polyvinylidene fluoride (PVDF) membrane and its derivative have been investigated the permeation ability for creatinine and urea. The membrane was made by an inversion precipitation system in N,N-dimethyl acetamide (DMAc) and water as non-solvents.
Retno Ariadi Lusiana   +8 more
doaj   +1 more source

Stochastic dynamics of remote knock-on permeation in biological ion channels [PDF]

open access: yes, 2013
Brownian dynamics simulations provide evidence for a remote knock-on mechanism facilitating the permeation of a biological ion channel by an ion that is initially trapped at the selectivity filter (SF).
P. V. E. McClintock   +13 more
core   +1 more source

Modelling the effect of mixture components on permeation through skin [PDF]

open access: yes, 2010
A vehicle influences the concentration of penetrant within the membrane, affecting its diffusivity in the skin and rate of transport. Despite the huge amount of effort made for the understanding and modelling of the skin absorption of chemicals, a ...
E.G. Samaras   +11 more
core   +1 more source

Human Skin Permeation Enhancement Using PLGA Nanoparticles Is Mediated by Local pH Changes

open access: yesPharmaceutics, 2021
The steady improvement and optimization of transdermal permeation is a constant and challenging pharmaceutical task. In this study the influence of poly(lactide-co-glycolide) (PLGA) nanoparticles on the dermal permeation of the anti-inflammatory drug ...
Javiana Luengo   +4 more
doaj   +1 more source

Development and characterization of niosomal gel of fusidic acid: in-vitro and ex-vivo approaches

open access: yesDesigned Monomers and Polymers, 2022
Niosomes are multilamellar vesicles that efficiently deliver active substance into skin systemic circulation or skin layers. They are used in topical drug delivery system to enhance the skin permeation of active substance. So, the prime objective of this
Muhammad Khurram Waqas   +9 more
doaj   +1 more source

Human Nails Permeation of an Antifungal Candidate Hydroalcoholic Extract from the Plant Sapindus saponaria L. Rich in Saponins

open access: yesMolecules, 2021
We evaluated a hydroalcoholic extract of Sapindus saponaria L. pericarps (ETHOSS), as a candidate to a topical antifungal medicine for onychomycosis. ETHOSS was produced by extracting the crushed fruits in ethanol.
Vanessa Mendes   +9 more
doaj   +1 more source

Surfactant and temperature effects on paraben transport through silicone membranes [PDF]

open access: yes, 2013
This study investigates the effects of two surfactants (one anionic and one non-ionic) and controlled modifications in temperature (298–323 K) on the permeation of two structurally similar compounds through a silicone membrane using a Franz diffusion ...
Bibi, Aisha   +4 more
core   +1 more source

Transdermal patch of acetylsalicylic acid as an alternative dosage form: A review [PDF]

open access: yesالمجلة العراقية للصيدلة, 2022
As a substitute for traditional systemic administration, many topical treatments have lately evolved. Transdermal drug delivery systems (TDDSs) are the most appealing of these methods due to their low rate of failure, simplicity of distribution, superior
Hayder Alhamdany, Mohanad Alfahad
doaj   +1 more source

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