Results 41 to 50 of about 168,330 (260)

Development of a Nanoemulgel for the Topical Application of Mupirocin

open access: yesPharmaceutics, 2023
Mupirocin (MUP) is an effective topical antibiotic with poor skin permeability; however, its skin permeability can be improved by a nanoemulsion formulation based on eucalyptus oil or eucalyptol. Despite this improvement, the nanoemulsion has limitations,
Bahjat Alhasso   +3 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Permeation-enhancing effects and mechanisms of O-acylterpineol on isosorbide dinitrate: mechanistic insights based on ATR-FTIR spectroscopy, molecular modeling, and CLSM images

open access: yes, 2019
The present study aimed to evaluate the penetration activity of O-acylterpineol derivatives both in vitro and in vivo, and to investigate the enhancing mechanism of O-acylterpineol derivatives which were synthesized by α-terpineol and fatty acid.
Chunyan Wang (306606)   +5 more
core   +1 more source

Permeation analysis of Liposomal gel.

open access: yes, 2021
Permeation analysis of Liposomal gel.
Arshad Khan (166346)   +7 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Synthesis and characterisation of TiO2 nanofibre/cellulose acetate nanocomposite ultrafiltration membrane

open access: yesJournal of Experimental Nanoscience, 2017
Nanofibres of TiO2 were synthesised by hydrothermal routine. Cellulose acetate/TiO2 nanofibre composite membranes were synthesised via blending TiO2 nanofibre in cellulose acetate solutions in 1-methyl-2-pyrrolidone.
Satya Deepika Neelapala   +2 more
doaj   +1 more source

Design and development of cefdinir niosomes for oral delivery

open access: yesJournal of Pharmacy and Bioallied Sciences, 2013
Objective: The aim of the present study was to develop nonionic surfactant based vesicles (niosomes) to improve poor and variable oral bioavailability of cefdinir.
Saurabh Bansal   +3 more
doaj   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

Wood Membrane Filter for Water Purification with Radial and Axial Flows

open access: yesBioResources, 2023
Water availability is an important issue all over the world, and membrane filtration technology is one of the most effective measures for remediation. As a sustainable and renewable biomass material, natural wood has a hierarchical and three-dimensional ...
Tong Su   +5 more
doaj   +2 more sources

Facilitated permeation of insulin across TR146 cells by cholic acid derivatives-modified elastic bilosomes

open access: yesInternational Journal of Nanomedicine, 2018
Santosh Bashyal,1 Jo-Eun Seo,1 Taekwang Keum,1 Gyubin Noh,1 Young Wook Choi,2 Sangkil Lee1 1College of Pharmacy, Keimyung University, Daegu, Republic of Korea; 2College of Pharmacy, Chung-Ang University, Seoul, Republic of Korea Background: Buccal ...
Bashyal S   +5 more
doaj  

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