Results 51 to 60 of about 275,207 (346)
Optimization of experimental conditions for skin-PAMPA measurements
ADMET and DMPK, 2020 In recent years, the parallel artificial membrane permeability assay (PAMPA) has been extended for prediction of skin permeation by developing an artificial membrane which mimics the stratum corneum structure, skin-PAMPA.
Sara Soriano-Meseguer +3 more
doaj +1 more source
Frontiers in Nutrition, 2022 Phosphates and trehalose are widely accepted additives in animal muscle products. In this study, the effects of pre-soaking with sodium tripolyphosphate (STPP) and trehalose under vacuum permeation (VP) conditions on the physicochemical properties of ...
Qi Du +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
GelsMicroemulsions have been commonly used with various permeation enhancers to improve permeability through the skin. The purpose of this study was to compare the release and permeation ability of two commonly used permeation enhancers—diethylene glycol ...
Sujata Pandey, Gabriella Baki
doaj +1 more source
Scientia Pharmaceutica, 2018 Superoxide dismutase (SOD) is an antioxidant protein. When administered orally, it has low bioavailability due to its low permeation. In a previous study we fused gliadin peptide P51 (LGQQQPFPPQQPYPQPQPF) and gliadin peptide P61 (QQPYPQPQPF) with SOD ...
Ratna Annisa Utami +3 more
doaj +1 more source
A Multi-Scale Approach to Model K+ Permeation Through the KcsA Channel
Frontiers in Molecular Biosciences, 2022 K+ channels allow a very efficient passage of K+ ions through the membrane while excluding Na+ ions, and these properties are essential for life. The 3D structure of the KcsA K+ channel, solved more than 20 years ago, allows to address many relevant ...
T. L. Horng +4 more
doaj +1 more source
Perspectives on Ion Permeation [PDF]
The Journal of General Physiology, 1999 The purpose of the Perspectives in General Physiology is to provide a forum where scientific uncertainties or controversies can be discussed in an authoritative, yet open manner. The Perspectives are solicited by the editors—often based on recommendations by the advisory editors or members of the editorial board, who may be asked to coordinate the ...
openaire +3 more sources
Hydrogen Permeation in Fusion Materials and the Development of Tritium Permeation Barriers
Plasma and Fusion Research, 2020 Fuel retention and hydrogen permeation in the first wall of future fusion devices are crucial factors. Due to safety issues and in order to guarantee an economical reactor operation, tritium accumulation into reactor walls and permeation through walls have to be estimated and prevented.
HOUBEN, Anne +2 more
openaire +3 more sources
FEBS Open Bio, EarlyView.Angubindin‐1 binds angulin‐1/‐3 at tricellular tight junctions, enhancing intestinal macromolecule permeation. Alanine scanning identified six essential residues (L562, L598, E638, V640, Y643, and K644) of angubindin‐1 critical for binding to angulin‐1/‐3 and permeation‐enhancing activity, providing insights for the development of targeted noninvasive ...
Taiki Kuzu +8 more
wiley +1 more source
Jurnal Kimia Sains dan AplikasiPolyvinyl alcohol (PVA) modified chitosan-carboxymethyl chitosan (CMC) membrane has been successfully fabricated and used as a dialysis membrane. This research aims to examine the manufacturing process, characterization, and dialysis performance of CMC ...
Riska Nurfirda Annisa +3 more
doaj +1 more source